Dna Encoded Chemical Libraries
DOWNLOAD
Download Dna Encoded Chemical Libraries PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Dna Encoded Chemical Libraries book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Dna Encoded Chemical Libraries
DOWNLOAD
Author : David Israel
language : en
Publisher: Springer Nature
Release Date : 2022-09-09
Dna Encoded Chemical Libraries written by David Israel and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-09 with Science categories.
This volume discusses protocols that cover synthesis, screening by selection, and analysis of DNA-encoded chemical libraries (DEL). Chapters in this book focus on methods used to practice DEL technology and include solution phase library synthesis using a variety of chemistries; DNA encoding of chemical structure; design, preparation and analysis of target proteins and tool compounds; screening of soluble protein targets by affinity selection; DEL qPCR, preparative PCR and DNA sequence analysis; computational methods used to analyze selections and choose compounds for resynthesis; and analysis of hit compounds. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, DNA-Encoded Chemical Libraries: Methods and Protocols is a valuable resource for scientists interested in DEL technology for drug discovery, and will contribute to the continued advancement in this important field.
Dna Encoded Chemical Libraries
DOWNLOAD
Author : Christoph Erich Dumelin
language : en
Publisher:
Release Date : 2007
Dna Encoded Chemical Libraries written by Christoph Erich Dumelin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.
A Handbook For Dna Encoded Chemistry
DOWNLOAD
Author : Robert A. Goodnow, Jr.
language : en
Publisher: John Wiley & Sons
Release Date : 2014-04-10
A Handbook For Dna Encoded Chemistry written by Robert A. Goodnow, Jr. and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-10 with Science categories.
This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry – synthetic and analytical chemistry, molecular biology, informatics, and biochemistry Shows medicinal and pharmaceutical chemists how to efficiently broaden available "chemical space" for drug discovery Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods
Dna Encoded Chemical Libraries
DOWNLOAD
Author : Luca Mannocci
language : en
Publisher:
Release Date : 2009
Dna Encoded Chemical Libraries written by Luca Mannocci and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.
Dna Encoded Libraries
DOWNLOAD
Author : Andreas Brunschweiger
language : en
Publisher: Springer Nature
Release Date : 2022-11-25
Dna Encoded Libraries written by Andreas Brunschweiger and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-25 with Science categories.
This book deals with the recent advances in DNA-Encoded Library (DEL) technology that has emerged as an alternative to high throughput screening (HTS) over the last decade and has been heralded as a "disruptive" technology for drug discovery. The book aims to provide a comprehensive overview of all of the major components of the DEL process from conception to bench execution and clinical investigations. The contributions from experts in the field combine different perspectives from academia and industry. The book will be of interest to researchers in the drug discovery field as well as to graduate students and scholars who are interested in this rapidly improving technology.
Dna Encoded Library Technology For Drug Discovery
DOWNLOAD
Author : Guansai Liu
language : en
Publisher: Royal Society of Chemistry
Release Date : 2025-02-21
Dna Encoded Library Technology For Drug Discovery written by Guansai Liu and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-21 with Science categories.
DNA-encoded libraries have numerous advantages over traditional screening methods, including easy identification of compounds and the large quantity of compounds that can be screened simultaneously. This book provides a comprehensive guide to the implementation of DNA-encoded library technology (DELT) in drug discovery for screening and hit validation, illustrated with successful case studies. A valuable resource for researchers in drug discovery, this book is complete with successful case studies to illustrate the best practice in implementation and operation of DELT.
Dna Encoded Chemical Libraries
DOWNLOAD
Author : Fabian Buller
language : en
Publisher:
Release Date : 2010
Dna Encoded Chemical Libraries written by Fabian Buller and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with categories.
Target Guided Selection Of Dna Encoded Chemical Libraries For Macrocycle Ligand Discovery
DOWNLOAD
Author : 林芳生
language : en
Publisher:
Release Date : 2023
Target Guided Selection Of Dna Encoded Chemical Libraries For Macrocycle Ligand Discovery written by 林芳生 and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023 with Combinatorial chemistry categories.
Nucleic Acids In Medicinal Chemistry And Chemical Biology
DOWNLOAD
Author : Lihe Zhang
language : en
Publisher: John Wiley & Sons
Release Date : 2023-01-05
Nucleic Acids In Medicinal Chemistry And Chemical Biology written by Lihe Zhang and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-05 with Science categories.
Nucleic Acids in Medicinal Chemistry and Chemical Biology An up-to-date and comprehensive exploration of nucleic acid medicinal chemistry and its applications In Nucleic Acids in Medicinal Chemistry and Chemical Biology: Drug Development and Clinical Applications, a team of distinguished researchers delivers a comprehensive overview of the chemistry and biology of nucleic acids and their therapeutic applications. The book emphasizes the latest research in the field, including new technologies like CRISPR that create novel possibilities to edit mutated genes at the genomic DNA level and to treat inherited diseases and cancers. The authors explore the application of modified nucleosides and nucleotides in medicinal chemistry, a variety of current topics on nucleic acid chemistry and biology, nucleic acid drugs used to treat disease, and more. They also probe new domains of pharmaceutical research, offering the reader a wealth of new drug discovery opportunities emerging in this dynamic field. Readers will also find: A thorough introduction to the basic terminology and knowledge of the field of nucleic acid medicinal chemistry Comprehensive explorations of the methods used to determine the development of nucleic acid drugs Practical discussions of new technologies, like CRISPR, nanotechnology-based delivery systems, synthetic biology, and DNA-encoded chemical libraries In-depth examinations of the latest, cutting-edge developments in nucleic acid medicinal chemistry Perfect for medicinal and nucleic acid chemists, Nucleic Acids in Medicinal Chemistry and Chemical Biology will also earn a place in the libraries of biochemists, chemical biologists, and pharmaceutical researchers.
Selection Of Dna Encoded Chemical Libraries Dels Against Cancer Cells Without Predefined Targets
DOWNLOAD
Author : 桂语晗
language : en
Publisher:
Release Date : 2024
Selection Of Dna Encoded Chemical Libraries Dels Against Cancer Cells Without Predefined Targets written by 桂语晗 and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024 with Combinatorial chemistry categories.