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Continuous Biomanufacturing


Continuous Biomanufacturing
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Continuous Biomanufacturing


Continuous Biomanufacturing
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Author : Ganapathy Subramanian
language : en
Publisher: John Wiley & Sons
Release Date : 2017-12-26

Continuous Biomanufacturing written by Ganapathy Subramanian and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-26 with Science categories.


This is the most comprehensive treatise of this topic available, providing invaluable information on the technological and economic benefits to be gained from implementing continuous processes in the biopharmaceutical industry. Top experts from industry and academia cover the latest technical developments in the field, describing the use of single-use technologies alongside perfusion production platforms and downstream operations. Special emphasis is given to process control and monitoring, including such topics as 'quality by design' and automation. The book is supplemented by case studies that highlight the enormous potential of continuous manufacturing for biopharmaceutical production facilities.



Process Control Intensification And Digitalisation In Continuous Biomanufacturing


Process Control Intensification And Digitalisation In Continuous Biomanufacturing
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Author : Ganapathy Subramanian
language : en
Publisher: John Wiley & Sons
Release Date : 2021-12-20

Process Control Intensification And Digitalisation In Continuous Biomanufacturing written by Ganapathy Subramanian and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-20 with Technology & Engineering categories.


Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing Explore new trends in continuous biomanufacturing with contributions from leading practitioners in the field With the increasingly widespread acceptance and investment in the ??technology, the last decade has demonstrated the utility of continuous ??processing in the pharmaceutical industry. In Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing, distinguished biotechnologist Dr. Ganapathy Subramanian delivers a comprehensive exploration of the potential of the continuous processing of biological products and discussions of future directions in advancing continuous processing to meet new challenges and demands in the manufacture of therapeutic products. A stand-alone follow-up to the editor’s Continuous Biomanufacturing: Innovative Technologies and Methods published in 2017, this new edited volume focuses on critical aspects of process intensification, process control, and the digital transformation of biopharmaceutical processes. In addition to topics like the use of multivariant data analysis, regulatory concerns, and automation processes, the book also includes: Thorough introductions to capacitance sensors to control feeding strategies and the continuous production of viral vaccines Comprehensive explorations of strategies for the continuous upstream processing of induced microbial systems Practical discussions of preparative hydrophobic interaction chromatography and the design of modern protein-A-resins for continuous biomanufacturing In-depth examinations of bioprocess intensification approaches and the benefits of single use for process intensification Perfect for biotechnologists, bioengineers, pharmaceutical engineers, and process engineers, Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing is also an indispensable resource for chemical engineers seeking a one-stop reference on continuous biomanufacturing.



Continuous Biomanufacturing In Microbial Systems


Continuous Biomanufacturing In Microbial Systems
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Author : Christoph Slouka
language : en
Publisher: Frontiers Media SA
Release Date : 2021-07-29

Continuous Biomanufacturing In Microbial Systems written by Christoph Slouka and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-29 with Science categories.


Christoph Herwig is founder of Exputec GmbH.



Emerging Technologies In Manufacturing


Emerging Technologies In Manufacturing
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Author : Matthew N. O. Sadiku
language : en
Publisher: Springer Nature
Release Date : 2023-03-15

Emerging Technologies In Manufacturing written by Matthew N. O. Sadiku and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-15 with Technology & Engineering categories.


The manufacturing industry is a cornerstone of national economy and people’s livelihood. It is the way of transforming resources into products or goods which are required to cater to the needs of the society. Traditional manufacturing companies currently face several challenges such as rapid technological changes, inventory problem, shortened innovation, short product life cycles, volatile demand, low prices, highly customized products, and ability to compete in the global markets. Modern manufacturing is highly competitive due to globalization and fast changes in the global market. This book reviews emerging technologies in manufacturing. These technologies include artificial intelligence, smart manufacturing, lean manufacturing, robotics, automation, 3D printing, nanotechnology, industrial Internet of things, and augmented reality. The use of these technologies will have a profound impact on the manufacturing industry. The book consists of 19 chapters. Each chapter addresses a single emerging technology in depth and describes how manufacturing organizations are adopting the technology. The book fills an important niche for manufacturing. It is a comprehensive, jargon-free introductory text on the issues, ideas, theories, and problems on emerging technologies in manufacturing. It is a must-read book for beginners or anyone who wants to be updated about emerging technologies.



Chemical And Bioprocess Engineering


Chemical And Bioprocess Engineering
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Author : Siddharth Venkatesh
language : en
Publisher: Educohack Press
Release Date : 2025-02-20

Chemical And Bioprocess Engineering written by Siddharth Venkatesh and has been published by Educohack Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-20 with Science categories.


"Chemical and Bioprocess Engineering: Innovations" is a comprehensive and accessible guide exploring the intricate world where chemistry and biology converge. Tailored for a global audience, with a focus on the United States, this book is an indispensable resource for students, professionals, and researchers in chemical and bioprocess engineering. The book demystifies complex concepts, offering a user-friendly journey through fundamental principles such as chemical engineering, thermodynamics, and fluid mechanics. Grounded in real-world applications, each chapter bridges theory and practice, emphasizing the role of chemical and bioprocess engineering in shaping the nation's technological landscape. Uniquely, this book addresses traditional chemical processes and delves into bioprocessing, covering genetic engineering, fermentation, and bioseparations. As the US leads in technological innovation, readers gain the knowledge and skills to navigate challenges and opportunities in chemical and biological processes. Emphasizing sustainability and green engineering, the book includes real-world case studies from diverse industries, highlighting eco-friendly practices. It integrates the latest advancements in bio-based materials, preparing the next generation of engineers for sustainable and ethical practices. Promoting a holistic understanding that transcends traditional boundaries, the book draws from biology, chemistry, and engineering. Exercises and practical examples in each chapter foster critical thinking and problem-solving skills, encouraging active contribution to the field. "Chemical and Bioprocess Engineering: Innovations" serves as a valuable reference for seasoned professionals and a companion for learners, keeping readers abreast of the latest developments in this ever-evolving field.



Bioprocess Intensification


Bioprocess Intensification
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Author : Dirk Holtmann
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2024-07-01

Bioprocess Intensification written by Dirk Holtmann and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-01 with Science categories.


Application of Process Intensification (PI) presents a set of radically innovative principles in process and equipment design, which can bring significant benefits in terms of process efficiency, capital and operating expenses, quality, process safety, and sustainability. Typical approaches in bioprocess intensification are the reduction of the number of production steps, continuous processing, integrated processes, and alternative energy inputs.



Cell Culture Engineering


Cell Culture Engineering
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Author : Gyun Min Lee
language : en
Publisher: John Wiley & Sons
Release Date : 2020-01-13

Cell Culture Engineering written by Gyun Min Lee and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-13 with Science categories.


Offers a comprehensive overview of cell culture engineering, providing insight into cell engineering, systems biology approaches and processing technology In Cell Culture Engineering: Recombinant Protein Production, editors Gyun Min Lee and Helene Faustrup Kildegaard assemble top class authors to present expert coverage of topics such as: cell line development for therapeutic protein production; development of a transient gene expression upstream platform; and CHO synthetic biology. They provide readers with everything they need to know about enhancing product and bioprocess attributes using genome-scale models of CHO metabolism; omics data and mammalian systems biotechnology; perfusion culture; and much more. This all-new, up-to-date reference covers all of the important aspects of cell culture engineering, including cell engineering, system biology approaches, and processing technology. It describes the challenges in cell line development and cell engineering, e.g. via gene editing tools like CRISPR/Cas9 and with the aim to engineer glycosylation patterns. Furthermore, it gives an overview about synthetic biology approaches applied to cell culture engineering and elaborates the use of CHO cells as common cell line for protein production. In addition, the book discusses the most important aspects of production processes, including cell culture media, batch, fed-batch, and perfusion processes as well as process analytical technology, quality by design, and scale down models. -Covers key elements of cell culture engineering applied to the production of recombinant proteins for therapeutic use -Focuses on mammalian and animal cells to help highlight synthetic and systems biology approaches to cell culture engineering, exemplified by the widely used CHO cell line -Part of the renowned "Advanced Biotechnology" book series Cell Culture Engineering: Recombinant Protein Production will appeal to biotechnologists, bioengineers, life scientists, chemical engineers, and PhD students in the life sciences.



Integrated Continuous Biomanufacturing A New Paradigm For Biopharmaceutical Production


Integrated Continuous Biomanufacturing A New Paradigm For Biopharmaceutical Production
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Author :
language : en
Publisher:
Release Date : 2015

Integrated Continuous Biomanufacturing A New Paradigm For Biopharmaceutical Production written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.




Genetic Engineering News


Genetic Engineering News
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Author :
language : en
Publisher:
Release Date : 2005

Genetic Engineering News written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Genetic engineering categories.




Mammalian Cell Perfusion Culture Development For Integrated Continuous Biomanufacturing


Mammalian Cell Perfusion Culture Development For Integrated Continuous Biomanufacturing
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Author : Daniel Johannes Karst
language : en
Publisher:
Release Date : 2016

Mammalian Cell Perfusion Culture Development For Integrated Continuous Biomanufacturing written by Daniel Johannes Karst and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with categories.