Septic Shock Methods And Protocols
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Septic Shock Methods And Protocols
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Author : Thomas J. Evans
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-01
Septic Shock Methods And Protocols written by Thomas J. Evans and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-01 with Medical categories.
Septic shock remains a serious medical condition with high mortality. Despite many advances in intensive care medicine and antibiotic devel- ment, this has not changed appreciably in the last 20 years. Frustratingly, over the same period of time, enormous advances have been made in understa- ing the underlying pathogenic mechanisms of this condition. This has resulted in the development of several novel therapies for septic shock, which, despite excellent theoretical grounds for their efficacy, have failed in altering mort- ity attributable to sepsis. The reasons for these failures are multiple, but it is clear that further research is required aimed at increasing our understanding of the basic pat- physiological processes that occur following infection. Research into septic shock draws upon a number of different disciplines, ranging from molecular and cellular biology to physiological measurements on whole animals. Septic Shock Methods and Protocols is an attempt to draw together into one volume a number of protocols that are of use in the investigation of the mechanisms of septic shock. I have divided the book into five sections. The first deals with endotoxin, the lipopolysaccharide component of the Gram-negative cell m- brane that can mimic many of the features of septic shock. Gram-positive organisms are found increasingly as causes of septic shock, and several - pects of toxins produced from these bacteria are considered in the second s- tion.
Molecular Pathology Of The Prions
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Author : Harry F. Baker
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02
Molecular Pathology Of The Prions written by Harry F. Baker and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Medical categories.
Internationally recognized investigators review the latest developments in, and novel approaches to, understanding the prion protein and prion diseases at the molecular level. Utilizing a variety of cutting-edge techniques, these distinguished scientists seek to define the normal function of a prion protein, to detect and measure the early immune response to prion disease, and to discover possible therapeutic targets. They also use transgenic mice and new electrophysiological investigations to elucidate the pathogenetic mechanisms involved in prion diseases. State-of-the-art and richly insightful, Molecular Pathology of the Prions captures for basic and clinical neuropathologists the latest developments and approaches to understanding the pathogenesis of prion diseases, and by analogy suggests possible research techniques for the more common proteinopthies, such as Alzheimer's and Parkinson's diseases.
Meningococcal Disease
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Author : Andrew J. Pollard
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02
Meningococcal Disease written by Andrew J. Pollard and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Medical categories.
Meningococcal septicemia and meningitis continue to be important causes of devastating illness, death, and long-term disability in both developed and resource-poor countries of the world. Few diseases have attracted as much public attention, or are as feared by parents and family members, as well as the medical staff who have to care for affected patients. The unexpected and unp- dictable occurrence of the disease in previously healthy children and young adults, its rapid progression, and the frequent occurrence of purpura fulminans with the resulting gangrene of limbs and digits and the requirement for mutilating s- gery, have all heightened both public and medical interest in the disease. Over the past two decades there has been a rapid increase in knowledge of many aspects of meningococcal disease as a result of intensive efforts by workers in many different fields: clinicians have studied the early presenting features and acute pathophysiology of the disorder; clinical scientists have explored the immunopathological mechanisms responsible for disease and have highlighted the important roles played by the host inflammatory response and pro-inflammatory cytokines in mediating damage to blood vessels and organs; microbiologists have developed new diagnostic methods; public health phy- cians and epidemiologists have improved surveillance techniques with the help of molecular tools provided by bacterial population biologists; and basic sci- tists have used the powerful new tools in molecular and cell biology to elucidate virulence mechanisms.
Molecular Analysis Of Cancer
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Author : Jacqueline Boultwood
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02
Molecular Analysis Of Cancer written by Jacqueline Boultwood and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Medical categories.
Over the past 20 years, technological advances in molecular biology have proven invaluable to the understanding of the pathogenesis of human cancer. The application of molecular technology to the study of cancer has not only led to advances in tumor diagnosis, but has also provided markers for the assessment of prognosis and disease progression. The aim of Molecular Ana- sis of Cancer is to provide a comprehensive collection of the most up-to-date techniques for the detection of molecular changes in human cancer. Leading researchers in the field have contributed chapters detailing practical pro- dures for a wide range of state-of-the-art techniques. Molecular Analysis of Cancer includes chapters describing techniques for the identification of chromosomal abnormalities and comprising: fluor- cent in situ hybridization (FISH), spectral karyotyping (SKY), comparative genomic hybridization (CGH), and microsatellite analysis. FISH has a pro- nent role in the molecular analysis of cancer and can be used for the detection of numerical and structural chromosomal abnormalities. The recently described SKY, in which all human metaphase chromosomes are visualized in specific colors, allows for the definition of all chromosomal rearrangements and marker chromosomes in a tumor cell. Protocols for the detection of chromosomal re- rangements by PCR and RT-PCR are described, as well as the technique of DNA fingerprinting, a powerful tool for studying somatic genetic alterations in tumorigenesis.
Year Book Of Critical Care Medicine 2011
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Author : R. Phillip Dellinger
language : en
Publisher: Elsevier Health Sciences
Release Date : 2011-05-15
Year Book Of Critical Care Medicine 2011 written by R. Phillip Dellinger and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-15 with Medical categories.
Year Book of Critical Care Medicine 2011
Critical Care Update 2023
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Author : Rajesh Chandra Mishra
language : en
Publisher: Jaypee Brothers Medical Publishers
Release Date : 2023-02-22
Critical Care Update 2023 written by Rajesh Chandra Mishra and has been published by Jaypee Brothers Medical Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-22 with Medical categories.
SECTION 1: Sepsis Diagnosis and Management 1. Precision Medicine in Septic Shock 2. Optimal Blood Pressure Target in Patients with Septic Shock 3. The Surviving Sepsis Campaign Guidelines in 2022: What is New and what has Changed? 4. Individualizing Hemodynamics in Septic Shock 5. Adjunctive Therapies in Sepsis: Current Status 6. Refractory Septic Shock: What are the Options 7. Steroids in Sepsis and Clinical Outcomes 8. Candida auris: Detection, Prevention, and Management 9. Empirical Antifungal Treatment: Is It Justified? 10. Role of Steroids in Severe Community acquired Pneumonia 11. Procalcitonin: Can It Differentiate Bacterial versus Fungal Infection SECTION 2: Antimicrobial Therapy in ICU 12. Optimizing Antimicrobial Dosing in the Intensive Care Unit 13. Antibiotic within 1 hour: Should this be Applied to all Patients with Sepsis? 14. Dark Side of Antibiotics 15. Optimal Duration of Antibiotic Therapy 16. Cefiderocol: Is this the Answer to Multidrug-resistant Gram-negative Infection? SECTION 3: Respiratory Critical Care 17. Management of Pneumonia in Intensive Care 18. Reverse Triggering during Controlled Ventilation: A Frequent Dysynchrony with Various Consequences 19. Use of Multiplex Polymerase Chain Reaction in Pneumonia 20. Management of Complicated Pleural Effusion 21. Hepatic Hydrothorax 22. Submassive Pulmonary Embolism 23. Role of Magnesium in Respiratory Failure 24. ARDS in Children: How is it Different? 25. Safe Tracheal Intubation in Intensive Care Unit 26. Lateral Positioning: Does it Work? 27. Dyspnea in Patients on Invasive Ventilation: Clinical Impact 28. Complications of Noninvasive Ventilation Failure SECTION 4: Mechanical Ventilation 29. Setting Optimum PEEP 30. Open Lung or Keep Lung Closed: Which Strategy to Choose? 31. Driving Pressure or Mechanical Power: Which One to Monitor? 32. Measuring Respiratory Drive and Muscle Effort 33. Oxygenation Targets in Mechanically Ventilated Critically-ill Patients 34. Ventilatory Ratio: A New Monitoring Tool 35. Helmet NIV: Is it a Game Changer? 36. Electrical Impedance Tomography: Current Application 37. Automatic Tube Compensation: Does it have a Role? 38. High-frequency Oscillatory Ventilation in Pediatric Acute Respiratory Distress Syndrome 39. Noninvasive Ventilation in Pediatrics: Current Status SECTION 5: Cardiovascular Critical Care 40. Crystalloid Resuscitation: Finding the Balance 41. Artificial Intelligence Tools to Optimize Hemodynamics in the ICU 42. Aggressive or Restrictive Fluid Resuscitation 43. Predicting Hypotension: Is It Useful? 44. Vasopressors: How Early? 45. Myocardial Injury after Noncardiac Surgery 46. Use of Vasopressin during Cardiac Arrest SECTION 6: Echocardiography and Ultrasound 47. Advances in Intensive Care Unit Echocardiography 48. Transesophageal Echocardiography: Is It Preferable in the Intensive Care Unit? 49. ECHO Features of Pulmonary Hypertension and Increased Left Atrial Pressures 50. Role of Echocardiography in Shock State 51. Use of Echocardiography in Assessing Fluid Responsiveness 52. Venous Excess Ultrasound Score (VExUS) SECTION 7: Nephrology, Fluids, Acid-Base Balance and Electrolytes Balance 53. Fluid Management in Acute Kidney Injury 54. Sepsis-associated Acute Kidney Injury: Common but Poorly Understood 55. Delayed versus Very Delayed Renal Replacement Therapy 56. Plasma Exchange in Intensive Care Unit: Current Status 57. Acute Kidney Injury Care Bundle 58. Biomarker-driven Therapy in AKI 59. How to Approach Dyselectrolytemias in a Patient on CRRT? SECTION 8: Neurocritical Care 60. Prognostication in
Forthcoming Books
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Author : Rose Arny
language : en
Publisher:
Release Date : 1999
Forthcoming Books written by Rose Arny and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with American literature categories.
The Gale Encyclopedia Of Nursing Allied Health P S
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Author : Kristine M. Krapp
language : en
Publisher: Gale Cengage
Release Date : 2002
The Gale Encyclopedia Of Nursing Allied Health P S written by Kristine M. Krapp and has been published by Gale Cengage this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
P S
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Author :
language : en
Publisher:
Release Date : 2002
P S written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with categories.
The Gale Encyclopedia Of Nursing Allied Health
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Author : Jacqueline L. Longe
language : en
Publisher: Gale Cengage
Release Date : 2006
The Gale Encyclopedia Of Nursing Allied Health written by Jacqueline L. Longe and has been published by Gale Cengage this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical categories.
Volume 1-5, covering entries A-Z, presents information on diseases and disorders, tests and procedures, body systems, health professions, and current health issues.