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Protein Microarrays


Protein Microarrays
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Protein Microarray Technology


Protein Microarray Technology
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Author : Dev Kambhampati
language : en
Publisher: John Wiley & Sons
Release Date : 2006-03-06

Protein Microarray Technology written by Dev Kambhampati and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-06 with Science categories.


This book is the first of its kind in the field of protein microarrays and addresses novel strategies for constructing highly functional and biocompatible microarrays for screening proteins. The list of authors consisting of world leading experts provide a roadmap for solving the complex challenges that are currently faced while monitoring protein-protein interactions over a wide range of microarray platforms. In doing so, they also offer a comprehensive overview of microarray surface chemistry, detection technologies, fabrication options for array development, and data analysis of numerous types of protein interactions. Topics covered include: -Types of biomolecular interactions -Surface chemistry -Detection technologies -Spotting technologies -Bioinformatics/data analysis. While primarily intended to serve as a reference for researchers and students embarking on the exciting fields of proteomics, drug discovery and clinical diagnostics, this technology is also expected to potentially impact the areas of food diagnostics, environmental monitoring and national security.



Protein Microarrays


Protein Microarrays
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Author : Mark Schena
language : en
Publisher: Jones & Bartlett Learning
Release Date : 2005

Protein Microarrays written by Mark Schena and has been published by Jones & Bartlett Learning this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Science categories.


Protein Microarrays is one of the first books in this exciting new technology and will be an essential reference for most biologists and biotechnology professionals.



Protein Microarray For Disease Analysis


Protein Microarray For Disease Analysis
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Author : Catherine J. Wu
language : en
Publisher: Humana Press
Release Date : 2011-08-25

Protein Microarray For Disease Analysis written by Catherine J. Wu and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-25 with Science categories.


Protein microarrays have been used for a wide variety of important tasks, such as identifying protein-protein interactions, discovering disease biomarkers, identifying DNA-binding specificity by protein variants, and for characterization of the humoral immune response. In Protein Microarray for Disease Analysis: Methods and Protocols, expert researchers provide concise descriptions of the methodologies currently used to fabricate microarrays for the comprehensive analysis of proteins or responses to proteins that can be used to dissect human disease. These methodologies are the toolbox for revolutionizing drug development and cell-level biochemical understanding of human disease processes. Beginning with a section on protein-detecting analytical microarrays, the volume continues with sections covering antigen microarrays for immunoprofiling, protein function microarrays, the validation of candidate targets, proteomic libraries, as well as signal detection strategies and data analysis techniques. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Practical and cutting-edge, Protein Microarray for Disease Analysis: Methods and Protocols serves as a solid framework to aid scientists in understanding how protein microarray technology is presently developing and how it can be applied to transform our analysis of human disease.



Protein Arrays


Protein Arrays
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Author : Eric Fung
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-03

Protein Arrays written by Eric Fung and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-03 with Science categories.


Protein Arrays: Methods and Protocols is an introduction to protein array technology and its application to the multiplexed detection of proteins. Although protein array technology has some roots in gene array technology, it can only be described as a distant relative. Unlike DNA, with its established rules of base pairing, and therefore predictable biochemical behavior, proteins are rich with diversity. Proteins can be large or small, compact or extended, basic or acidic, hydrophobic or hydrophilic, and so on. Just as importantly, their behavior is determined by the environment in which they reside, and so the composition of the buffer in which experiments are performed has a dramatic impact on the outcome of the experiment. Thus, if the goal is to simultaneously measure the expression of a large number of proteins, these variables must be addressed. Not to be deterred, scientists have created a variety of solutions to successfully detect and ch- acterize multiple proteins simultaneously. It is the intent of this volume to introduce to the reader a set of technological solutions to the diversity problem as well as to provide the reader with some examples of practical applications of these technologies.



Functional Protein Microarrays In Drug Discovery


Functional Protein Microarrays In Drug Discovery
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Author : Paul F. Predki
language : en
Publisher: CRC Press
Release Date : 2007-03-30

Functional Protein Microarrays In Drug Discovery written by Paul F. Predki and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-30 with Medical categories.


An ideal text for biotechnologists, protein chemists, and biochemists, Functional Protein Microarrays in Drug Discovery explores all aspects of functional protein microarrays, including basic principles, methods, and applications. The book discusses the generation of functional protein content and describes both standard and state-of-the-art fabrication methods. It reviews current and next generation approaches to assay detection and presents a wide range of applications, from biomolecular interaction discovery and characterization to immune response profiling. The book also addresses several fundamental computational issues, bioinformatics and data analysis.



Protein Microarrays For Disease Analysis


Protein Microarrays For Disease Analysis
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Author : Rodrigo Barderas
language : en
Publisher: Humana
Release Date : 2021-07-11

Protein Microarrays For Disease Analysis written by Rodrigo Barderas and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-11 with Science categories.


This volume focuses on protein analysis, and covers a wide array of uses of protein microarray for disease analysis. The chapters in this book discuss different stages of protein microarrays from their construction to their use, including different types of protein microarrays such as recombinant proteins, antibody, phage, and NAPPA protein microarrays, in planar format or in solution via beads arrays. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Protein Microarrays for Disease Analysis: Methods and Protocols is a valuable resource for graduate and post-doctoral fellows interested in protein microarrays, as well as senior researchers interested in gaining more insight into this developing field.



Protein Microarray Technology


Protein Microarray Technology
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Author : Dev Kambhampati
language : en
Publisher: Wiley-Blackwell
Release Date : 2004-03

Protein Microarray Technology written by Dev Kambhampati and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-03 with Medical categories.


Protein microarrays soon will become one of the major tools for realizing the goals of drug discovery research in the post-genome era. The book is aimed at life science researchers and scientists working in drug and pharma industry.



The Development Of Proteosep And Protein Microarrays As Well As Their Applications To Cancer Proteomics With Mass Spectrometric Methods


The Development Of Proteosep And Protein Microarrays As Well As Their Applications To Cancer Proteomics With Mass Spectrometric Methods
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Author : Fang Yan
language : en
Publisher:
Release Date : 2003

The Development Of Proteosep And Protein Microarrays As Well As Their Applications To Cancer Proteomics With Mass Spectrometric Methods written by Fang Yan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.




Protein Microarrays


Protein Microarrays
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Author : Ulrike Korf
language : en
Publisher: Humana Press
Release Date : 2011-08-19

Protein Microarrays written by Ulrike Korf and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-19 with Science categories.


Progress in functional proteomics has been limited for a long time, partially caused by limitations in assay sensitivity and sample capacity; however, protein microarrays have the ability to overcome these limitations so that a highly parallel analysis of hundreds of proteins in thousands of samples is attainable. In Protein Microarrays: Methods and Protocols, expert researchers in the field present an up-to-date collection of robust strategies in the field of protein microarrays and summarize recent advantages in the field of printing technologies, the development of suitable surface materials, as well as detection and quantification technologies. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key notes on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Protein Microarrays: Methods and Protocols aims to stimulate the application and further advancement of this powerful technology in labs worldwide.



Applying Genomic And Proteomic Microarray Technology In Drug Discovery Second Edition


Applying Genomic And Proteomic Microarray Technology In Drug Discovery Second Edition
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Author : Robert S. Matson
language : en
Publisher: CRC Press
Release Date : 2013-03-13

Applying Genomic And Proteomic Microarray Technology In Drug Discovery Second Edition written by Robert S. Matson and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-13 with Medical categories.


Microarrays play an increasingly significant role in drug discovery. The commercial landscape has changed dramatically over the past few years and researchers have made great advancements with regard to construction and use. Now in its second edition, Applying Genomic and Proteomic Microarray Technology in Drug Discovery highlights, describes, and evaluates current scientific research using microarray technology in genomic and proteomic applications. Updated and revised to reflect recent progress in the field, the second edition discusses: Expanded omics-driven applications, including the areas of metabolomics and chemical biology The commercialization of the microarray platform, with a historical perspective aimed at recognizing key technological developments Solid-supports (substrates) and surface chemistries currently used in the creation of nucleic acid and protein microarrays Different approaches to producing microarrays that achieve spot equality with the same number of molecules properly oriented The development of the gene expression microarray and representative applications The development of protein microarray technology, including its history and key applications Unique to this edition is a new chapter on multiplex assays that examines the development and applications of arrays across diverse platforms. It discusses applications for qPCR, multiplex lateral flow, and multiplex bead assays. It also presents platform-to-platform comparisons. Microarrays remain an invaluable tool for omics-based research not only in drug discovery, but in the life sciences, in clinical research, and for diagnostic applications worldwide. This volume presents the current state of the art on the utility of this technology to solve a host of important biological problems.