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Protein Bioinformatics


Protein Bioinformatics
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Protein Bioinformatics


Protein Bioinformatics
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Author : M. Michael Gromiha
language : en
Publisher: Academic Press
Release Date : 2010-09-08

Protein Bioinformatics written by M. Michael Gromiha and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-08 with Computers categories.


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Protein Bioinformatics


Protein Bioinformatics
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Author : Ingvar Eidhammer
language : en
Publisher: John Wiley & Sons
Release Date : 2004-02-13

Protein Bioinformatics written by Ingvar Eidhammer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-02-13 with Mathematics categories.


Pairwise global alignment of sequences. Pairwise local alignment and database search. Statical analysis. Multiple global alignment and phylogenetic trees. Scoring matrices. Profiles. Sequence patterns. Structures and structure descriptions. Superposition and Dynamic programming. Geometric techniques. Clustering: Combining local similarities. Significance and assessment of structure comparisons. Multiple structure comparison. Protein structure classification. Structure prediction: Threading. Basics in mathematics, probability and algorithms. Introduction to molecular biology.



Large Language Models Llms In Protein Bioinformatics


Large Language Models Llms In Protein Bioinformatics
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Author : Dukka B. KC
language : en
Publisher: Springer Nature
Release Date : 2025-07-02

Large Language Models Llms In Protein Bioinformatics written by Dukka B. KC and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-02 with Computers categories.


This book presents a comprehensive collection of methods, resources, and studies that use large language models (LLMs) in the field of protein bioinformatics. Reflecting the swift pace of LLM development today, the volume delves into numerous LLM-based tools to investigate proteins science, from protein language models to the prediction of protein-ligand binding sites. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice to ensure success in future research. Authoritative and practical, Large Language Models (LLMs) in Protein Bioinformatics serves as an ideal guide for scientists seeking to tap into the potential of artificial intelligence in this vital area of biological study.



Protein Bioinformatics


Protein Bioinformatics
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Author : Frédérique Lisacek
language : en
Publisher: Springer Nature
Release Date : 2024-07-12

Protein Bioinformatics written by Frédérique Lisacek and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-12 with Computers categories.


This detailed volume explores techniques for protein bioinformatics research, including databases, software tools, and computational methods, in the context of protein science or proteomics and opening to other omics areas. Beginning with a section on proteogenomics, the book continues by covering posttranslational modifications, processing large-scale mass spectrometry data, protein structure and interactions, as well as protein feature inference. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice to ensure efficacious results. Authoritative and practical, Protein Bioinformatics serves as an ideal guide for researchers in disciplines encompassing the biotechnological, pharmaceutical, biological, and medical sciences, as well as the computational and engineering sciences.



The Ten Most Wanted Solutions In Protein Bioinformatics


The Ten Most Wanted Solutions In Protein Bioinformatics
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Author : Anna Tramontano
language : en
Publisher: CRC Press
Release Date : 2005-05-24

The Ten Most Wanted Solutions In Protein Bioinformatics written by Anna Tramontano and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-05-24 with Mathematics categories.


Utilizing high speed computational methods to extrapolate to the rest of the protein universe, the knowledge accumulated on a subset of examples, protein bioinformatics seeks to accomplish what was impossible before its invention, namely the assignment of functions or functional hypotheses for all known proteins.The Ten Most Wanted Solutions in Pro



Algorithmic And Artificial Intelligence Methods For Protein Bioinformatics


Algorithmic And Artificial Intelligence Methods For Protein Bioinformatics
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Author : Yi Pan
language : en
Publisher: John Wiley & Sons
Release Date : 2013-10-07

Algorithmic And Artificial Intelligence Methods For Protein Bioinformatics written by Yi Pan and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-07 with Medical categories.


Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics An in-depth look at the latest research, methods, and applications in the field of protein bioinformatics This book presents the latest developments in protein bioinformatics, introducing for the first time cutting-edge research results alongside novel algorithmic and AI methods for the analysis of protein data. In one complete, self-contained volume, Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics addresses key challenges facing both computer scientists and biologists, arming readers with tools and techniques for analyzing and interpreting protein data and solving a variety of biological problems. Featuring a collection of authoritative articles by leaders in the field, this work focuses on the analysis of protein sequences, structures, and interaction networks using both traditional algorithms and AI methods. It also examines, in great detail, data preparation, simulation, experiments, evaluation methods, and applications. Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics: Highlights protein analysis applications such as protein-related drug activity comparison Incorporates salient case studies illustrating how to apply the methods outlined in the book Tackles the complex relationship between proteins from a systems biology point of view Relates the topic to other emerging technologies such as data mining and visualization Includes many tables and illustrations demonstrating concepts and performance figures Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics is an essential reference for bioinformatics specialists in research and industry, and for anyone wishing to better understand the rich field of protein bioinformatics.



Scalable Big Data Analytics For Protein Bioinformatics


Scalable Big Data Analytics For Protein Bioinformatics
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Author : Dariusz Mrozek
language : en
Publisher: Springer
Release Date : 2018-09-25

Scalable Big Data Analytics For Protein Bioinformatics written by Dariusz Mrozek and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-25 with Computers categories.


This book presents a focus on proteins and their structures. The text describes various scalable solutions for protein structure similarity searching, carried out at main representation levels and for prediction of 3D structures of proteins. Emphasis is placed on techniques that can be used to accelerate similarity searches and protein structure modeling processes. The content of the book is divided into four parts. The first part provides background information on proteins and their representation levels, including a formal model of a 3D protein structure used in computational processes, and a brief overview of the technologies used in the solutions presented in the book. The second part of the book discusses Cloud services that are utilized in the development of scalable and reliable cloud applications for 3D protein structure similarity searching and protein structure prediction. The third part of the book shows the utilization of scalable Big Data computational frameworks, like Hadoop and Spark, in massive 3D protein structure alignments and identification of intrinsically disordered regions in protein structures. The fourth part of the book focuses on finding 3D protein structure similarities, accelerated with the use of GPUs and the use of multithreading and relational databases for efficient approximate searching on protein secondary structures. The book introduces advanced techniques and computational architectures that benefit from recent achievements in the field of computing and parallelism. Recent developments in computer science have allowed algorithms previously considered too time-consuming to now be efficiently used for applications in bioinformatics and the life sciences. Given its depth of coverage, the book will be of interest to researchers and software developers working in the fields of structural bioinformatics and biomedical databases.



Practical Protein Bioinformatics


Practical Protein Bioinformatics
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Author : Florencio Pazos
language : en
Publisher: Springer
Release Date : 2014-11-28

Practical Protein Bioinformatics written by Florencio Pazos and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-28 with Science categories.


This book describes more than 60 web-accessible computational tools for protein analysis and is totally practical, with detailed explanations on how to use these tools and interpret their results and minimal mentions to their theoretical basis (only when that is required for making a better use of them). It covers a wide range of tools for dealing with different aspects of proteins, from their sequences, to their three-dimensional structures, and the biological networks they are immersed in. The selection of tools is based on the experience of the authors that lead a protein bioinformatics facility in a large research centre, with the additional constraint that the tools should be accessible through standard web browsers without requiring the local installation of specific software, command-line tools, etc. The web tools covered include those aimed to retrieve protein information, look for similar proteins, generate pair-wise and multiple sequence alignments of protein sequences, work with protein domains and motifs, study the phylogeny of a family of proteins, retrieve, manipulate and visualize protein three-dimensional structures, predict protein structural features as well as whole three-dimensional structures, extract biological information from protein structures, summarize large protein sets, study protein interaction and metabolic networks, etc. The book is associated to a dynamic web site that will reflect changes in the web addresses of the tools, updates of these, etc. It also contains QR codes that can be scanned with any device to direct its browser to the tool web site. This monograph will be most valuable for researchers in experimental labs without specific knowledge on bioinformatics or computing.



High Performance Computational Solutions In Protein Bioinformatics


High Performance Computational Solutions In Protein Bioinformatics
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Author : Dariusz Mrozek
language : en
Publisher: Springer
Release Date : 2014-06-04

High Performance Computational Solutions In Protein Bioinformatics written by Dariusz Mrozek and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-04 with Science categories.


Recent developments in computer science enable algorithms previously perceived as too time-consuming to now be efficiently used for applications in bioinformatics and life sciences. This work focuses on proteins and their structures, protein structure similarity searching at main representation levels and various techniques that can be used to accelerate similarity searches. Divided into four parts, the first part provides a formal model of 3D protein structures for functional genomics, comparative bioinformatics and molecular modeling. The second part focuses on the use of multithreading for efficient approximate searching on protein secondary structures. The third and fourth parts concentrate on finding 3D protein structure similarities with the support of GPUs and cloud computing. Parts three and four both describe the acceleration of different methods. The text will be of interest to researchers and software developers working in the field of structural bioinformatics and biomedical databases.



Machine Learning In Bioinformatics Of Protein Sequences Algorithms Databases And Resources For Modern Protein Bioinformatics


Machine Learning In Bioinformatics Of Protein Sequences Algorithms Databases And Resources For Modern Protein Bioinformatics
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Author : Lukasz Kurgan
language : en
Publisher: World Scientific
Release Date : 2022-12-06

Machine Learning In Bioinformatics Of Protein Sequences Algorithms Databases And Resources For Modern Protein Bioinformatics written by Lukasz Kurgan and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-06 with Science categories.


Machine Learning in Bioinformatics of Protein Sequences guides readers around the rapidly advancing world of cutting-edge machine learning applications in the protein bioinformatics field. Edited by bioinformatics expert, Dr Lukasz Kurgan, and with contributions by a dozen of accomplished researchers, this book provides a holistic view of the structural bioinformatics by covering a broad spectrum of algorithms, databases and software resources for the efficient and accurate prediction and characterization of functional and structural aspects of proteins. It spotlights key advances which include deep neural networks, natural language processing-based sequence embedding and covers a wide range of predictions which comprise of tertiary structure, secondary structure, residue contacts, intrinsic disorder, protein, peptide and nucleic acids-binding sites, hotspots, post-translational modification sites, and protein function. This volume is loaded with practical information that identifies and describes leading predictive tools, useful databases, webservers, and modern software platforms for the development of novel predictive tools.