Population Genomics
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Population Genomics
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Author : Om P. Rajora
language : en
Publisher: Springer
Release Date : 2019-01-07
Population Genomics written by Om P. Rajora and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-07 with Science categories.
Population genomics has revolutionized various disciplines of biology including population, evolutionary, ecological and conservation genetics, plant and animal breeding, human health, medicine and pharmacology by allowing to address novel and long-standing questions with unprecedented power and accuracy. It employs large-scale or genome-wide genetic information and bioinformatics to address various fundamental and applied aspects in biology and related disciplines, and provides a comprehensive genome-wide perspective and new insights that were not possible before. These advances have become possible due to the development of new and low-cost sequencing and genotyping technologies and novel statistical approaches and software, bioinformatics tools, and models. Population genomics is tremendously advancing our understanding the roles of evolutionary processes, such as mutation, genetic drift, gene flow, and natural selection, in shaping up genetic variation at individualloci and across the genome and populations; improving the assessment of population genetic parameters or processes such as adaptive evolution, effective population size, gene flow, admixture, inbreeding and outbreeding depression, demography, and biogeography; resolving evolutionary histories and phylogenetic relationships of extant, ancient and extinct species; understanding the genomic basis of fitness, adaptation, speciation, complex ecological and economically important traits, and disease and insect resistance; facilitating forensics, genetic medicine and pharmacology; delineating conservation genetic units; and understanding the genetic effects of resource management practices, and assisting conservation and sustainable management of genetic resources. This Population Genomics book discusses the concepts, approaches, applications and promises of population genomics in addressing most of the above fundamental and applied crucial aspects in a variety of organisms from microorganisms to humans. The book provides insights into a range of emerging population genomics topics including population epigenomics, landscape genomics, seascape genomics, paleogenomics, ecological and evolutionary genomics, biogeography, demography, speciation, admixture, colonization and invasion, genomic selection, and plant and animal domestication. This book fills a vacuum in the field and is expected to become a primary reference in Population Genomics world-wide.
Population Genomics Wildlife
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Author : Paul A. Hohenlohe
language : en
Publisher: Springer Nature
Release Date : 2020-12-09
Population Genomics Wildlife written by Paul A. Hohenlohe and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-09 with Science categories.
Population genomics is revolutionizing wildlife biology, conservation, and management by providing key and novel insights into genetic, population and landscape-level processes in wildlife, with unprecedented power and accuracy. This pioneering book presents the advances and potential of population genomics in wildlife, outlining key population genomics concepts and questions in wildlife biology, population genomics approaches that are specifically applicable to wildlife, and application of population genomics in wildlife population and evolutionary biology, ecology, adaptation and conservation and management. It is important for students, researchers, and wildlife professionals to understand the growing set of population genomics tools that can address issues from delineation of wildlife populations to assessing their capacity to adapt to environmental change. This book brings together leading experts in wildlife population genomics to discuss the key areas of the field, as well as challenges, opportunities and future prospects of wildlife population genomics.
Population Genomics Crop Plants
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Author : Om P. Rajora
language : en
Publisher: Springer Nature
Release Date : 2024-06-08
Population Genomics Crop Plants written by Om P. Rajora and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-08 with Science categories.
Population genomics has revolutionized several disciplines of biology, genetic resource conservation and management, and breeding of crop plants by providing key and novel insights into population, evolutionary, ecological and conservation genetics, ecology, evolution and adaptation, and facilitating molecular breeding with an unprecedented power and accuracy. Crop plants have been domesticated from their wild progenitors over several centuries and have undergone severe genetic bottlenecks and selection sweeps. Population genomics research has unraveled novel insights into crop plants origin, evolution, demographic history, center of diversity, domestication history, genetic/genomic diversity and genetic structure of wild and domesticated populations and species, epigenomic diversity, genetic/genomic basis of domestication syndrome, genomic footprints of domestication, selection and breeding, de-domestication, speciation and admixture, taxonomy, phylogeny, ecology, biotic and abiotic stress tolerance, and ecological and climate adaptation. Population genomics has also facilitated the development of pangenomes, conservation and management of genetic diversity including in the pre-breeding and breeding programs, and genomics-assisted breeding via identifying genotype-phenotype associations and genomic selection in crop plants. This pioneering book presents the advances made and potential of population genomics in addressing the above crop plants aspects of basic and applied significance and brings together leading experts in crop plants population genomics to discuss these topics in major crop plants. Genomic, epigenomic, transcriptomic and plant resources available for population genomics research and challenges, opportunities and future perspectives of crop plants population genomics are also discussed. Chapters "Population Genomics of Yams: Evolution and Domestication of Dioscorea Species" and "Population Genomics Along With Quantitative Genetics Provides a More Efficient Valorization of Crop Plant Genetic Diversity in Breeding and Pre-breeding Programs" are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Population Genomics Marine Organisms
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Author : Marjorie F. Oleksiak
language : en
Publisher: Springer Nature
Release Date : 2019-12-31
Population Genomics Marine Organisms written by Marjorie F. Oleksiak and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-31 with Science categories.
Population genomics has provided unprecedented opportunities to unravel the mysteries of marine organisms in the oceans' depths. The world's oceans, which make up 70% of our planet, encompass diverse habitats and host numerous unexplored populations and species. Population genomics studies of marine organisms are rapidly emerging and have the potential to transform our understanding of marine populations, species, and ecosystems, providing insights into how these organisms are evolving and how they respond to different stimuli and environments. This knowledge is critical for understanding the fundamental aspects of marine life, how marine organisms will respond to environmental changes, and how we can better protect and preserve marine biodiversity and resources. This book brings together leading experts in the field to address critical aspects of fundamental and applied research in marine species and share their research and insights crucial for understanding marine ecosystem diversity and function. It also discusses the challenges, opportunities and future perspectives of marine population genomics.
Population Genomics With R
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Author : Emmanuel Paradis
language : en
Publisher: CRC Press
Release Date : 2020-05-05
Population Genomics With R written by Emmanuel Paradis and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-05 with Mathematics categories.
Population Genomics With R presents a multidisciplinary approach to the analysis of population genomics. The methods treated cover a large number of topics from traditional population genetics to large-scale genomics with high-throughput sequencing data. Several dozen R packages are examined and integrated to provide a coherent software environment with a wide range of computational, statistical, and graphical tools. Small examples are used to illustrate the basics and published data are used as case studies. Readers are expected to have a basic knowledge of biology, genetics, and statistical inference methods. Graduate students and post-doctorate researchers will find resources to analyze their population genetic and genomic data as well as help them design new studies. The first four chapters review the basics of population genomics, data acquisition, and the use of R to store and manipulate genomic data. Chapter 5 treats the exploration of genomic data, an important issue when analysing large data sets. The other five chapters cover linkage disequilibrium, population genomic structure, geographical structure, past demographic events, and natural selection. These chapters include supervised and unsupervised methods, admixture analysis, an in-depth treatment of multivariate methods, and advice on how to handle GIS data. The analysis of natural selection, a traditional issue in evolutionary biology, has known a revival with modern population genomic data. All chapters include exercises. Supplemental materials are available on-line (http://ape-package.ird.fr/PGR.html).
Human Population Genomics
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Author : Kirk E. Lohmueller
language : en
Publisher: Springer Nature
Release Date : 2021-03-13
Human Population Genomics written by Kirk E. Lohmueller and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-13 with Science categories.
This textbook provides a concise introduction and useful overview of the field of human population genomics, making the highly technical and contemporary aspects more accessible to students and researchers from various fields. Over the past decade, there has been a deluge of genetic variation data from the entire genome of individuals from many populations. These data have allowed an unprecedented look at human history and how natural selection has impacted humans during this journey. Simultaneously, there have been increased efforts to determine how genetic variation affects complex traits in humans. Due to technological and methodological advances, progress has been made at determining the architecture of complex traits. Split in three parts, the book starts with the basics, followed by more advanced and current research. The first part provides an introduction to essential concepts in population genetics, which are relevant for any organism. The second part covers the genetics of complex traits in humans. The third part focuses on applying these techniques and concepts to genetic variation data to learn about demographic history and natural selection in humans. This new textbook aims to serve as a gateway to modern human population genetics research for those new to the field. It provides an indispensable resource for students, researchers and practitioners from disparate areas of expertise.
Drosophila Population Genomics
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Author : Andrew David Kern
language : en
Publisher:
Release Date : 2005
Drosophila Population Genomics written by Andrew David Kern and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.
Statistical Population Genomics
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Author : Julien Y. Dutheil
language : en
Publisher:
Release Date : 2020
Statistical Population Genomics written by Julien Y. Dutheil and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Bioinformatics categories.
This open access volume presents state-of-the-art inference methods in population genomics, focusing on data analysis based on rigorous statistical techniques. After introducing general concepts related to the biology of genomes and their evolution, the book covers state-of-the-art methods for the analysis of genomes in populations, including demography inference, population structure analysis and detection of selection, using both model-based inference and simulation procedures. Last but not least, it offers an overview of the current knowledge acquired by applying such methods to a large variety of eukaryotic organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, pointers to the relevant literature, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Statistical Population Genomics aims to promote and ensure successful applications of population genomic methods to an increasing number of model systems and biological questions.
Population Genomics Microorganisms
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Author : Martin F. Polz
language : en
Publisher: Springer
Release Date : 2019-01-07
Population Genomics Microorganisms written by Martin F. Polz and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-07 with Science categories.
Population genomics is a rapidly emerging field that has the potential to transform our understanding of how evolutionary forces shape genomic diversity among microbes. There have already been considerable advances in understanding gene flow and spread of adaptive traits, and in linking epidemiology with evolutionary biology. The current challenge is to find unifying evolutionary principles for organisms that display a wide range of reproductive biology – from highly clonal to promiscuous – and for which the vast majority have eluded cultivation. This requires interdisciplinary approaches that incorporate novel computational tools, testing of existing and novel population genetic models, and creative new ways of linking genetic diversity to ecological factors. This pioneering book will discuss the advances made and promises of population genomics in microorganisms, outlining some of the key theoretical and practical challenges for microbial population genomics, including defining and identifying populations, genomics-based reverse ecology and building appropriate tools to understand microbes in a variety of complex environments.
Data Production And Analysis In Population Genomics
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Author : Fran Ois Pompanon
language : en
Publisher: Humana Press
Release Date : 2016-05-01
Data Production And Analysis In Population Genomics written by Fran Ois Pompanon and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-01 with Medical categories.
This book details protocols and methods that are applicable to species where genomic resources are scarce. It addresses how to implement the best method to obtain the required data given constraints as well as the other genetic resources already available.