Pharmacogenomics
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Pharmacogenomics
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Author : Werner Kalow
language : en
Publisher: CRC Press
Release Date : 2001-05-08
Pharmacogenomics written by Werner Kalow and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-05-08 with Medical categories.
"Summarizes the history of, and available applications, techniques, and approaches to, pharmacogenomics--improving efficacy and tolerance to pharmaceutical compounds, evaluating pharmacogenomics on clinical trial design, and increasing the chances of successful clinical trials and patient outcomes. Compares pharmacogenomics to pharmacogenetics, focusing on the essential components that incorporate individual genetic variations to drug regimens resulting in different responses to therapeutics."
Genomics Driven Drug Discovery Through Pharmacogenomics
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Author : Parikesit, Arli Aditya
language : en
Publisher: IGI Global
Release Date : 2024-12-13
Genomics Driven Drug Discovery Through Pharmacogenomics written by Parikesit, Arli Aditya and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-13 with Medical categories.
Genetic diseases and disorders are common factors in modern pharmacogenomics. The study of emerging factors in epigenomics are significant for effective drug discovery and formulation, as well as for balancing pharmacological and ethical factors in drug development. The goal of drug discovery is to recognize the new molecular formulations impactful in the treatment of genetic diseases. Further exploration of the move from preclinical drug research to the clinical stage may reveal critical transformations to provide effective medicinal products in the market. As precision medicine evolves, genomics-driven drug discovery may also improve patient outcomes while reducing the trial-and-error approach to prescribing medications, assisting with individualized, targeted healthcare. Genomics-Driven Drug Discovery Through Pharmacogenomics explores the integration of genomics into drug discovery and development in the pharmacogenomics field. It offers effective solutions to address challenges of personalized healthcare, ethical dilemmas, and technological considerations involved in drug discovery. This book covers topics such as medical technology, personalized medicine, and drug development, and is a useful resource for medical professionals, healthcare workers, computer engineers, scientists, pharmacologists, academicians, and researchers.
Pharmacogenomics
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Author : Showkat Ahmad Ganie
language : en
Publisher: Elsevier
Release Date : 2023-06-13
Pharmacogenomics written by Showkat Ahmad Ganie and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-13 with Medical categories.
Pharmacogenomics: From Discovery to Clinical Implementation is a complete reference aimed at building a solid foundation of the key concepts in this fast-moving knowledge area. The editors lined up a group of worldwide experts to contribute to the book. Following a consistent chapter structure, the authors cover the foundational aspects of pharmacogenomics in the first four chapters of the book that include basic concepts, drug metabolism, drug discovery and development, and testing. The second part of the book is dedicated to detailed studies of key health conditions and the potential therapeutic applications of pharmacogenomics. Diseases covered include diabetes, cardiovascular diseases, psychiatric disease, cancer, pulmonary and respiratory diseases, viral diseases, gastroenterology, autoimmune diseases, immunosuppressants, and, finally, an overview of computational resources. Pharmacogenomics: From Discovery to Clinical Implementation is the perfect resource for pharmaceutical science graduate students to learn the key concepts of the area. Researchers and graduate students in the related fields of Genetics, pharmacoepidemiology, molecular biology, and medicinal chemistry will also benefit of the structured approach of the book. - Provides an in-depth review of pharmacogenomics and its role in drug discovery/metabolism and its clinical impacts - Describes the practice of pharmacogenomics in the treatment of diabetes, cancers, cardiovascular diseases, psychiatric disorders, pulmonary diseases, infectious, gastroenterology, and autoimmune diseases - Uses a consistent chapter structure to support understanding of the fundamental concepts in the area
Principles Of Pharmacogenetics And Pharmacogenomics
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Author : Russ B. Altman
language : en
Publisher: Cambridge University Press
Release Date : 2012-01-23
Principles Of Pharmacogenetics And Pharmacogenomics written by Russ B. Altman and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-23 with Medical categories.
This textbook presents the latest information on pharmacogenetics and pharmacogenomics for students, professionals and researchers.
Pharmacogenomics An Introduction And Clinical Perspective
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Author : Joseph S. Bertino
language : en
Publisher: McGraw Hill Professional
Release Date : 2012-10-12
Pharmacogenomics An Introduction And Clinical Perspective written by Joseph S. Bertino and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-12 with Medical categories.
A COMPLETE INTRODUCTORY TEXT TO THE FIELD OF PHARMACOGENOMICS The only pharmacogenomics resource to feature a global author team comprised of PharmDs, MDs, PhDs and social scientists, Pharmacogenomics offers an essential, highly accessible survey of this dynamic discipline. You will find thorough coverage of all need-to-know topics, from individual molecules to systemic diseases, plus an examination of the latest technologies that are constantly reshaping the field. Pharmacogenomics is cohesively organized into two sections, the first of which reviews basic aspects of pharmacogenomics, including ethics, regulatory, science, and drug metabolism, along with a "mini" course in molecular genetics and testing. The second section highlights the practical application of pharmacogenomics in cardiovascular medicine, immunology, neurology, and other specialties. FEATURES Important overview of general pharmacogenomics and pharmacogenetics concepts, including genetic variation in signal transduction and targets, plus a review of the genetic concepts of pharmacogenomics Discussion of regulatory considerations in pharmacogenomics Focus on the role of health care professionals along with a review of related privacy issues, as well as broader ethical, legal, and social considerations In-depth chapters on drug metabolism and transporters Practical, step-by-step guidance on public access to pharmacogenomic testing and patient counseling Up-to-date coverage of non-genetic influences on pharmacogenomics Emphasis on gene-drug interactions Numerous tables and figures Chapter-ending references Concise learning objectives at the beginning of each chapter Case studies to familiarize you with the clinical relevance of pharmacogenomics in each specialty
Pharmacogenomics
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Author : Mark A. Rothstein
language : en
Publisher: John Wiley & Sons
Release Date : 2003-04-09
Pharmacogenomics written by Mark A. Rothstein and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-04-09 with Science categories.
Through analyses of the complex underlying issues, this interdisciplinary volume frames the agenda for dealing with genetic variation and incorporating pharmacogenomics into health care. The three sections of this book, Research Issues, Clinical Issues, and Social Perspectives address key elements integral to a comprehensive discussion of this emerging field. This groundbreaking text... Examines new research strategies, methodologies, and ethical and social considerations of pharmacogenomics Addresses practical considerations of anticipated changes in education, training, oversight, guidelines and protocols, and continuing education requirements Provides analyses of the potential enormous impact of pharmacogenomics, such as in the standard of care and treatment, including perspectives from the fields of anthropology, law, ethics, and economics
Pharmacogenomics In Precision Medicine
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Author : Weimin Cai
language : en
Publisher: Springer Nature
Release Date : 2020-06-12
Pharmacogenomics In Precision Medicine written by Weimin Cai and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-12 with Medical categories.
This book provides an introduction to the principles of pharmacogenomics and precision medicine, followed by the pharmacogenomics aspects of major therapeutic areas such as cardiovascular disease, cancer, organ transplantation, psychiatry, infection, antithrombotic drugs. It also includes genotyping technology and therapeutic drug monitoring in Pharmacogenomics; ethical, Legal and Regulatory Issues; cost-effectiveness of pharmacogenetics-guided treatment; application of pharmacogenomics in drug discovery and development and clinical Implementation of Pharmacogenomics for Personalized Precision Medicine. The contributors of Pharmacogenomics in Precision Medicine come from a team of experts, including professors from academic institutions and practitioner from hospital. It will give an in-depth overview of the current state of pharmacogenomics in drug therapy for all health care professionals and graduate students in the era of precision medicine.
Pharmacogenomics An Introduction And Clinical Perspective
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Author : Joseph S. Bertino
language : en
Publisher: McGraw Hill Professional
Release Date : 2013
Pharmacogenomics An Introduction And Clinical Perspective written by Joseph S. Bertino and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Medical categories.
Pharmacogenomics is comprehensive textbook detailing how genetic makeup affects a body's response to drugs.
Pharmacogenomics In Psychiatry
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Author : Matthias Schwab
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2010-01-01
Pharmacogenomics In Psychiatry written by Matthias Schwab and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-01 with Medical categories.
In recent years, there have been major developments in the fields of pharmacogenetics and pharmacogenomics, with the potential to make drug treatments in psychiatric medicine more effective. However, improvements in drug efficacy and tolerability, as well as finding the optimal dosage, can only be realized if in vivo mechanisms of drug action and ADME (absorption, distribution, metabolism, excretion) processes (pharmacokinetics) of psychopharmacological agents are better understood. In this volume, current progress and perspectives in pharmacogenetic testing of drug-metabolizing enzymes, drug transporters and other drug targets involved in the response to psychotropic agents are described extensively. This provides a timely overview of what has been achieved in the area of psychiatric pharmacogenomics alongside some promising directions and perspectives for future research. Psychiatrists, general medical doctors as well as pharmacologists and clinical pharmacologists will find new insights into the development and applications of pharmacogenomics in psychiatry.
Pharmacogenomics
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Author : Yui-Wing Francis Lam
language : en
Publisher: Academic Press
Release Date : 2013-02-12
Pharmacogenomics written by Yui-Wing Francis Lam and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-12 with Science categories.
Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation includes discussions and viewpoints from the academic, regulatory, pharmaceutical, clinical, socio-ethical and economic perspectives. Each chapter presents an overview of the potential or opportunity within the areas discussed and also outlines foreseeable challenges and limitations in moving pharmacogenomics into drug development and direct therapeutic applications. This edited book contains review questions for a more in-depth analysis of the implications of pharmacogenomics and discussion points to generate ideas on best to move the field forward. Clinical pearls and case studies are used to illustrate real-life experiences and both successful and unsuccessful applications. Tables, figures, and annotations are included throughout the book to facilitate understanding and further reference. - Multi-contributed book and chapters are written by contributors who are experts in their field - Provides perspectives from those involved in all aspects of pharmacogenomics—including academic, regulatory, economic, industry and medical—to illustrate how all of the pieces fit together and where the challenges may be - Includes case studies of both successful and unsuccessful applications so readers can consider the potential and challenges in moving the science into drug development and direct therapeutic applications - Chapters contain discussion questions and clinical pearls and enable readers to reflect on how to move pharmacogenomics forward and apply these observations and useful tips to their own work and research