Multiplex Biomarker Techniques
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Multiplex Biomarker Techniques
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Author : Paul C. Guest
language : en
Publisher:
Release Date : 2016
Multiplex Biomarker Techniques written by Paul C. Guest and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Biochemical markers categories.
"This detailed book arrives as there is an increasing need for multiplex biomarker readouts for improved clinical management and to support the development of new drugs by pharmaceutical companies, due to continuous technical developments and new insights into the high complexity of many diseases. Chapters explore the basic technology platforms being applied in the fields of genomics, proteomics, transcriptomics, metabolomics, and imaging, which are currently the methods of choice in multiplex biomarker research. The book also describes the chief medical areas in which the greatest progress has been made and highlight areas where further resources are required. Written for the highly successful Methods in Molecular Biology series, methodology chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Multiplex Biomarker Techniques: Methods and Applications serves as an ideal resource for a wide variety of researchers interested in these vital multiplex techniques."--Springer.
Multiplex Biomarker Techniques
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Author : Paul C. Guest
language : en
Publisher: Springer Nature
Release Date : 2022-07-15
Multiplex Biomarker Techniques written by Paul C. Guest and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-15 with Medical categories.
This detailed volume explores the application of multiplex biomarker methods in the critical area of COVID-19 research through state-of-the-art technologies in the fields of genomics, proteomics, transcriptomics, metabolomics, and imaging. The book features a series of protocols from labs across the globe employing multiplex molecular approaches, which can be applied to accelerate progress in the research of SARS-CoV-2 and other infectious illnesses. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and essential, Multiplex Biomarker Techniques: Methods and Applications for COVID-19 Disease Diagnosis and Risk Stratification serves as a vital resource for researchers in the areas of virology, metabolic diseases, respiratory disorders, as well as to clinical scientists, physicians, pharmacologists, and the healthcare services.
Application Of Omic Techniques To Identify New Biomarkers And Drug Targets For Covid 19
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Author : Paul C. Guest
language : en
Publisher: Springer Nature
Release Date : 2023-06-28
Application Of Omic Techniques To Identify New Biomarkers And Drug Targets For Covid 19 written by Paul C. Guest and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-28 with Medical categories.
The COVID-19 pandemic caused by the SARS-CoV-2 virus has affected nearly every country and territory in the world. Although worldwide vaccination efforts have reduced the risk of serious disease outcomes, disparities in distribution have led to multiple waves of SARS-CoV-2 outbreaks and the emergence of variants of concern, some of which have enhanced infectivity and ability to evade existing vaccines. Hence there is an increasing interest in understanding the evolution of viruses like SARS-CoV-2, as well as improving our capacity to effectively current and manage future pandemics. This new volume reviews the most effective omic techniques for increasing our understanding of COVID-19, to improve diagnostics, prognostics, and genomic surveillance, and to facilitate development of effective treatments and vaccines. Chapters are written by an international team of experts and explore methods in the areas of genomics, transcriptomics, proteomics, and metabolomics. Techniques used to assess physiological function at the molecular level and artificial intelligence approaches used for more effective validation and translation of biomarker candidates into clinical use are also discussed. This book is an excellent resource for researchers studying biomarkers, virology, metabolic diseases, and infectious diseases, as well as clinical scientists, physicians, drug company scientists, and healthcare workers.
Laboratory Techniques In Cellular And Molecular Medicine
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Author : Hajdúch, Marián
language : en
Publisher: Palacky University Olomouc
Release Date :
Laboratory Techniques In Cellular And Molecular Medicine written by Hajdúch, Marián and has been published by Palacky University Olomouc this book supported file pdf, txt, epub, kindle and other format this book has been release on with Medical categories.
The methodological book ""Laboratory techniques in cellular and molecular medicine"" is intended for students of bachelor, master, and doctoral study programmes at faculties of science, medicine, and veterinary medicine, as well as for laboratory technicians interested in methodological approaches of contemporary cellular and molecular medicine. The book does not aim to provide a comprehensive overview of the current state of the art in cellular and molecular medicine, that would be a superhuman task. The aim of the 56-member author team is to provide readers with an overview of the methods established and tested at the Institute of Molecular and Translational Medicine of the Faculty of Medicine of Palacký University Olomouc – to describe the methodological principles and their practical application. It focuses both on basic methods, whose principles are used by the most modern methods, and on special methods, reflecting the laboratory experience and specialisation of individual authors. The 52 chapters describe the work with cells and microorganisms, bioengineering manipulations of nucleic acids, the search for biomarkers, detection at the level of DNA, RNA, protein, organelle, and whole cell, and the use of fluorescent and radioactive labeling. To aid comprehension, the description of the methods is illustrated by figures and diagrams. Each chapter is followed by troubleshooting tips. The book promotes the best laboratory practice to increase the reproducibility of results in biomedicine.
Proteomic Methods In Neuropsychiatric Research
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Author : Paul C. Guest
language : en
Publisher: Springer
Release Date : 2017-03-28
Proteomic Methods In Neuropsychiatric Research written by Paul C. Guest and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-28 with Science categories.
Due to continuous technical developments and new insights into the high complexity of neurological diseases, there is an increasing need for the application of proteomic technologies which can yield potential biomarker readouts for improved clinical management as well as for the development of new drugs by struggling pharmaceutical companies. This book describes the step-by-step use of proteomic methods such as two-dimensional gel electrophoresis, multiplex immunoassay, liquid chromatography mass spectrometry (LC-MS) and selective reaction monitoring MS, to increase our understanding of these diseases, with the ultimate aim of improving patient care. The volume will be of high interest to clinical scientists, physicians and pharmaceutical company scientists as it gives insights into the latest technologies enabling the revolution of personalized medicine. It is of direct interest to both technical and bench biomarker scientists as it gives step by step instructions on how to carry out each of the protocols. It is also of interest to researchers as each technique will be presented in the context of a specific neurological disorder, including Alzheimer's disease, multiple sclerosis, autism spectrum disorders, schizophrenia, major depressive disorder and bipolar disorder. Finally, it will also highlight the future research efforts in this field, which are endeavoring to convert proteomic platforms to the form of hand held devices which can be used in a point of care setting and return diagnostic results within the timeframe of a visit to the general practitioner.
Protein Arrays
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Author : Cristina Ruiz-Romero
language : en
Publisher: Springer Nature
Release Date : 2025-07-02
Protein Arrays written by Cristina Ruiz-Romero and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-02 with Science categories.
This volume discusses the latest methods and applications of protein microarrays and helps researchers harness its power in their work. The chapters in this book explore protein microarray’s development and fabrication, strategies for their data analysis, and wide-reaching applications in biology and disease research. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Protein Arrays: Methods and Protocols is a valuable resource for graduate students, postdoctoral researchers, laboratory scientists, and industry professionals who wish to learn more about protein microarray technology. Chapter 3 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Multiplex Microarrays For Diagnosis And Detection
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Author : Bradley H. Garcia
language : en
Publisher:
Release Date : 2008
Multiplex Microarrays For Diagnosis And Detection written by Bradley H. Garcia and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.
Genetic Engineering Biotechnology News
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Author :
language : en
Publisher:
Release Date : 2009
Genetic Engineering Biotechnology News written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Biotechnology categories.
Basic Science Of Oncology Fifth Edition
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Author : Ian F. Tannock
language : en
Publisher: McGraw Hill Professional
Release Date : 2013-09-22
Basic Science Of Oncology Fifth Edition written by Ian F. Tannock and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-22 with Medical categories.
NOW IN FULL COLOR! Discover the science of cancer--with this newly revised, essential introduction to cancer biology and genetics Here in one well-organized, reader-friendly volume, you'll find everything you must know about the biology underlying cancer and its treatment, supported by the latest peer-reviewed research. Written by preeminent oncology researchers and clinicians, the book highlights the full range of important oncology topics and takes you through the biological basis of current and future biological therapy as well as more traditional approaches to cancer treatment. Presented in full color, the Fifth Edition of The Basic Science of Oncology is thoroughly updated and refreshed to reflect the latest critical thinking in oncology. For graduate students, oncologists, residents, and fellows, there can be no more useful guide to the bedrock science and practice of oncology than this all-in-one reference. FEATURES: The most current, evidence-based oncology primer--one that encapsulates the science of cancer causation, cancer biology, and cancer therapy Key insights into molecular and genetic aspects of cancer familiarize you with cancer biology as applied to prognosis and personalized cancer medicine In-depth focus on the discovery, evaluation, and biology of anti-cancer drugs, immunotherapy, and molecularly-targeted agents Up-to-date coverage of the basic science of radiation therapy Specific chapters/sections on intratumor heterogeneity as it relates to potential new treatment strategies--including tumor microenvironment and metabolism, tumor stem cells, and genomic/proteomic heterogeneity NEW! Chapter Essentials synthesize chapter content in a convenient list NEW! Color diagrams and schematics summarize important data
A Rapid Multiplexed Diagnostic System For Breast Cancer
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Author : Rupa Srikant Rao
language : en
Publisher:
Release Date : 2006
A Rapid Multiplexed Diagnostic System For Breast Cancer written by Rupa Srikant Rao and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with categories.