Molecular Diagnostics
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Fundamentals Of Molecular Diagnostics
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Author : David E. Bruns
language : en
Publisher: Saunders
Release Date : 2007
Fundamentals Of Molecular Diagnostics written by David E. Bruns and has been published by Saunders this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
This book offers an introduction to the newest, fastest-growing field in laboratory science. Explaining and clarifying the molecular techniques used in diagnostic testing, this text provides both entry-level and advanced information. It covers the principles of molecular biology along with genomes and nucleic acid alterations, techniques and instrumentation, and applications of molecular diagnostics. Written by leading experts, including Patrick Bossuyt, Angela Caliendo, Rossa W.K. Chiu, Kojo S.J. Elenitoba-Johnson, Andrea Ferreira-Gonzalez, Amy Groszbach, Sultan Habeebu, Doris Haverstick, Malek Kamoun, Anthony Killeen, Noriko Kusukawa, Y.M. Dennis Lo, Elaine Lyon, Gwendolyn McMillin, Christopher Price, James Versalovic, Cindy Vnencak-Jones, Victor Weedn, Peter Wilding, Thomas Williams, and Carl Wittwer, this book includes illustrations, tables, and a colorful design to make information easy to find and easy to use. A full-color, 4-page insert shows realistic images of the output for many molecular tests. Learning Objectives open each chapter with an overview of what you should achieve. Key Words are listed and defined at the beginning of each chapter, and are bolded in the text. Review Questions at the end of every chapter let you measure your comprehension. Advanced Concepts are included, but set apart from the rest of the text, for students who want a higher level of learning. Ethics boxes address ethical issues, allowing you to apply your knowledge to real-life scenarios. A glossary of all key words may be easily accessed in the back of the book.
Molecular Diagnostics
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Author : Gregory J. Tsongalis
language : en
Publisher: Amer. Assoc. for Clinical Chemistry
Release Date : 2002
Molecular Diagnostics written by Gregory J. Tsongalis and has been published by Amer. Assoc. for Clinical Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
Molecular Diagnostics Promises And Possibilities
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Author : Mousumi Debnath
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-01-29
Molecular Diagnostics Promises And Possibilities written by Mousumi Debnath and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-29 with Medical categories.
A rapid development in diverse areas of molecular biology and genetic engineering resulted in emergence of variety of tools. These tools are not only applicable to basic researches being carried out world over, but also exploited for precise detection of abnormal conditions in plants, animals and human body. Although a basic researcher is well versed with few techniques used by him/her in the laboratory, they may not be well acquainted with methodologies, which can be used to work out some of their own research problems. The picture is more blurred when the molecular diagnostic tools are to be used by physicians, scientists and technicians working in diagnostic laboratories in hospitals, industry and academic institutions. Since many of them are not trained in basics of these methods, they come across several gray areas in understanding of these tools. The accurate application of molecular diagnostic tools demands in depth understanding of the methodology for precise detection of the abnormal condition of living body. To meet the requirements of a good book on molecular diagnostics of students, physicians, scientists working in agricultural, veterinary, medical and pharmaceutical sciences, it needs to expose the reader lucidly to: Give basic science behind commonly used tools in diagnostics Expose the readers to detailed applications of these tools and Make them aware the availability of such diagnostic tools The book will attract additional audience of pathologists, medical microbiologists, pharmaceutical sciences, agricultural scientists and veterinary doctors if the following topics are incorporated at appropriate places in Unit II or separately as a part of Unit-III in the book. Molecular diagnosis of diseases in agricultural crops Molecular diagnosis of veterinary diseases. Molecular epidemiology, which helps to differentiate various epidemic strains and sources of disease outbreaks. Even in different units of the same hospital, the infections could be by different strains of the same species and the information becomes valuable for infection control strategies. Drug resistance is a growing problem for bacterial, fungal and parasitic microbes and the molecular biology tools can help to detect the drug resistance genes without the cultivation and in vitro sensitivity testing. Molecular diagnostics offers faster help in the selection of the proper antibiotic for the treatment of tuberculosis, which is a major problem of the in the developing world. The conventional culture and drug sensitivity testing of tuberculosis bacilli is laborious and time consuming, whereas molecular diagnosis offers rapid drug resistant gene detection even from direct clinical samples. The same approach for HIV, malaria and many more diseases needs to be considered. Molecular diagnostics in the detection of diseases during foetal life is an upcoming area in the foetal medicine in case of genetic abnormalities and infectious like TORCH complex etc. The book will be equally useful to students, scientists and professionals working in the field of molecular diagnostics.
Molecular Diagnostics
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Author : George P. Patrinos
language : en
Publisher: Elsevier
Release Date : 2005-06-06
Molecular Diagnostics written by George P. Patrinos and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-06-06 with Science categories.
Molecular Diagnostics covers current molecular biological techniques used to identify the underlying molecular defects in inherited disease. Although an increasing number of laboratories, both academic and private are moving in that direction, there are only a few books in the existing literature, and they deal only partly with diagnosis at the molecular level. Each chapter includes the principle and a brief description of the technique, followed by exmples from the authors' own epertise. Contributors are well-known experts in their field, and derive from a variety of disciplines, to ensure breadth and depth of coverage. - Examines widely used molecular biology techniques to screen for genetic defects causing inherited disorders - Includes state-of-the-art techniques for the detection of the underlying genetic heterogeneity leading to inherited disorders - Identification of genetically modified organisms (GMO's) - Forensic analysis and every-day issues in a diagnostic laboratory - Discusses ethics, genetic counselling and quality management
Molecular Diagnostics
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Author : William B. Coleman
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-28
Molecular Diagnostics written by William B. Coleman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-28 with Medical categories.
Accompanying CD-ROM contains ... "a companion eBook version of Molecular diagnostics : for the clinical laboratorian, Second edition ... for downloading and use in the reader's PC or PDA."--Page 4 of cover.
Molecular Diagnostics
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Author : Jim F. Huggett
language : en
Publisher: Caister Academic Press Limited
Release Date : 2014
Molecular Diagnostics written by Jim F. Huggett and has been published by Caister Academic Press Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Medical categories.
The application of molecular technology in clinical diagnosis is a rapidly developing area and is predicted to greatly improve the speed, efficiency, and accuracy of diagnostic medicine. The editors of this book have commissioned an excellent series of chapters representing two key molecular diagnostic areas: cancer and infectious diseases. The cancer section deals with the challenges in identifying genetic, epigenetic, and transcriptomic biomarkers. The infectious disease section describes the current clinical applications of molecular diagnostics for the detection of viral, bacterial, and fungal pathogens, as well as an example of the use of molecular diagnostics outside the clinic environment. A cautionary tale describing what can go wrong when molecular methods are applied incorrectly is also provided and makes fascinating reading. A substantial component of the book is dedicated to the process of translating a preclinical test to the bedside and describes the progress in the near patient point-of-care molecular diagnostics market. This is a fundamental consideration for successful translation of diagnostics tests from bench to bedside and is crucial for molecular diagnostics to have an impact on patient care. The final chapter offers a prediction of future trends in the molecular diagnostics of infectious diseases. This volume is essential reading for anyone involved in the development or application of molecular diagnostics and is recommended for all clinical diagnostics laboratories. [Subject: Medicine, Molecular Biology, Epidemiology, Life Science, Oncology]
Molecular Diagnostics
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Author : Lela Buckingham
language : en
Publisher: F.A. Davis
Release Date : 2019-02-22
Molecular Diagnostics written by Lela Buckingham and has been published by F.A. Davis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-22 with Medical categories.
Meet the challenges of this rapidly expanding field with a solid understanding of the fundamentals of nucleic acid biochemistry as well as the advanced concepts integral to practice in today’s laboratories. With a focus on the application of molecular concepts to the diagnosis of disease, the 3rd Edition of this popular resource encompasses microbiology, virology, genetics, oncology, and human identification.
Clinical Molecular Diagnostics
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Author : Shiyang Pan
language : en
Publisher: Springer
Release Date : 2022-07-23
Clinical Molecular Diagnostics written by Shiyang Pan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-23 with Medical categories.
This book covers the discovery of molecular biomarkers, the development of laboratory testing techniques and their clinical applications, focusing on basic research to clinical practice. It introduces new and crucial knowledge and ethics of clinical molecular diagnosis. This book emphasizes the applications of clinical molecular diagnostic test on health management, especially from different diseased organs. It lets readers to understand and realize precision healthcare.
Molecular Diagnostics
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Author : E. van Pelt-Verkuil
language : en
Publisher: Springer
Release Date : 2019-06-03
Molecular Diagnostics written by E. van Pelt-Verkuil and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-03 with Medical categories.
The books Molecular Diagnostics Part 1 and 2 provide a comprehensive and practical overview of the state-of-the-art molecular biological diagnostic strategies that are being used in a wide variety of disciplines. The editors and experts in their respective fields have combined their knowledge to write these two books. Many years of experience in the development, application and quality control of molecular diagnostic methods is reflected herewith. Molecular Diagnostics Part 1 is dedicated to the theoretical backgrounds of the technologies often applied in molecular diagnostics, in which nucleic acid amplification methods (such as real-time PCR), sequencing and bioinformatics are the basic tools. The assay design and -development, combined with items of trouble-shooting are described in detail. As a foundation of reliable molecular diagnostic assays, the quality control required for validation, implementation and performance of molecular diagnostic assays is thoroughly discussed. This book also provides extensive information for those working with molecular techniques in a wide variety of research applications using conventional and real-time PCR technology, Sanger and high throughput sequencing techniques, and bioinformatics. Molecular Diagnostics Part 2 highlights the applications of the molecular diagnostic methods in the various diagnostic laboratories, comprising: - Clinical microbiology - Clinical chemistry - Clinical genetics - Clinical pathology - Molecular hematopathology - Veterinary health - Plant health - Food safety Both full-colour and well-illustrated books are particularly valuable for students, clinicians, scientists and other professionals who are interested in (designing) molecular diagnostic methods and for those who wish to broaden their knowledge on the current molecular biological revolution. The information in the books highlights the trend ofthe integration of multiple (clinical) disciplines into one universal molecular laboratory.
Techniques In Molecular Diagnostics
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Author : Kandarpa Kr. Saikai
language : en
Publisher: New India Publishing Agency
Release Date : 2016-09-23
Techniques In Molecular Diagnostics written by Kandarpa Kr. Saikai and has been published by New India Publishing Agency this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-23 with Science categories.
The book covers from the very basic introduction on molecular biology and diagnostics to the protocols of advanced assays that can be offered by a diagnostic laboratory. There is detailed description on the requirements for setting up a laboratory. The chapter on laboratory mathematics will help the reader in preparation of common laboratory solutions. The book contains basic protocols to perform nucleic acid extraction from different sources. These protocols can be effortlessly applied to isolate high quality DNA and RNA from human blood and tissues. The book is profusely explained with various molecular diagnostic tools which are easy to understand and can be applied in diagnosis of different cancers. This book also presents with examples of biomarker detection protocols for specific cancer type using molecular diagnostic tools which can easily be reproduced. These protocols are very sensitive, cost effective and can be performed to provide faster and accurate diagnosis. The last part of the book deliberates on the quality assurance and quality control strategies of a molecular diagnostic laboratory. Special emphasis is made on specific guidelines to design quality manuals for a molecular diagnostic laboratory