Insight On Genotoxicity

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Insight On Genotoxicity

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Author : Shiv Shankar Shukla
language : en
Publisher: CRC Press
Release Date : 2020-10-14

Insight On Genotoxicity written by Shiv Shankar Shukla and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-14 with Science categories.

Genetic toxicology is considered to be an important assessment tool as there is genetic impact of artificial chemicals. Insight on Genotoxicity discusses testing, mechanism, prediction, and bioindicator of genotoxicity taking into consideration recent advances in nano-engineered particles. Corollary of DNA dent is also discussed in detail taking into consideration the impact of ICH guidelines on genotoxicity testing, which is important for drug discovery innovation and development. Perspective review of genotoxicity evaluation in phytopharmaceuticals has been mentioned along with the prevention of genotoxicity in brief viewpoint. Salient Features Presents methods, standard protocols, and guidelines for genotoxicity testing Examines the impact of ICH Guidelines on genetic toxicity testing which is a regulatory requirement for drug discovery and development Defines appropriate strategies about advances in in vivo genotoxicity testing which have been listed along with progress and prospects Discusses advancement in the high-throughput approaches for genotoxicity testing Details computational prediction of genotoxicity with consideration of mutagenicity, chromosomal damage caused and strategies for computational prediction in drug development

Elucidating The Mechanism Of Chromium Genotoxicity

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Author : Zhanna Sobol
language : en
Publisher:
Release Date : 2007

Elucidating The Mechanism Of Chromium Genotoxicity written by Zhanna Sobol and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.

The Cancer Handbook 2 Volume Set

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Author : Malcolm Alison
language : en
Publisher: John Wiley & Sons
Release Date : 2007-07-30

The Cancer Handbook 2 Volume Set written by Malcolm Alison and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-30 with Medical categories.

The Cancer Handbook provides a comprehensive overview of scientific and clinical information in cancer research and medicine (oncology). This area is one of the most intensively studied in biology and medicine, resulting in a huge amount of new information being published every year. This book summarizes and explains key facts and recent developments. It is aimed at a wide variety of readers who need easy access to knowledge concerning all major aspects of cancer biology, without too much clinical detail or specialist research material. The Cancer Handbook stands out from existing oncology textbooks and reference works in that it bridges the gap between the molecular biology of cancer and clinical diagnosis and treatment. As more and more laboratory research is applied to clinical management, e.g. the use of monoclonal antibodies as drugs, it is important that clinicians understand the aetiology of the disease and the molecular basis of the new therapeutic approaches. It is also important for laboratory scientists to appreciate the potential applications of their research and the practical issues involved in translating it to clinical practice. For this second edition, all the sections have been fully revised and updated, with new chapters addressing important topics that have gained prominence in recent years. New editors and authors have brought additional expertise to the project. For example, in the section on the Molecular and Cellular Basis of Cancer, there are new chapters on stem cells, epigenetics, and microRNAs, as well as chapters on the links between cancer and development and inflammation. In the Treatment section, the emphasis is now on multidisciplinary team management of different cancers, plus there are new chapters on clinical trial design, RNA interference and rational drug design. The page design and the quality of the diagrams has been improved, with all illustrations now in full colour. The glossary has been made more informative and easy to use.

Handbook Of Genotoxic Effects And Fish Chromosomes

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Author : Kabil Al-Sabti
language : en
Publisher:
Release Date : 1991

Handbook Of Genotoxic Effects And Fish Chromosomes written by Kabil Al-Sabti and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Chromosome abnormalities categories.

Comprehensive Toxicology Toxicological Testing And Evaluation

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Author : I. Glenn Sipes
language : en
Publisher:
Release Date : 1997

Comprehensive Toxicology Toxicological Testing And Evaluation written by I. Glenn Sipes and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Poisoning categories.

This volume in the Comprehensive Toxicology series demonstrates how the use of extremely powerful molecular and cell biology techniques has stimulated the growth of toxicology as a scientific discipline. The field of toxicology has evolved from its earlier days of in vivo and descriptive studies to focusing on mechanisms. Frequently, mechanisms require an examination at the cellular and molecular level. Molecular toxicology has opened the door to comprehending the basic mechanisms of how toxicants show their effects. The volume is a comprehensive, integrated profile of the molecular effects of toxicants and the molecular mechanisms involved in producing cellular and tissue injury.

Toxicological Profile For Aldrin Dieldrin

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Author : Department of Health & Human Services.September 2002
language : en
Publisher:
Release Date : 2002

Toxicological Profile For Aldrin Dieldrin written by Department of Health & Human Services.September 2002 and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with categories.

Indicators Of Genotoxic Exposure

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Author : B. A. Bridges
language : en
Publisher: Cold Spring Harbor Laboratory Press
Release Date : 1982

Indicators Of Genotoxic Exposure written by B. A. Bridges and has been published by Cold Spring Harbor Laboratory Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Medical categories.

Toxicological Profile For Aldrin Dieldrin

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Author :
language : en
Publisher:
Release Date : 2002

Toxicological Profile For Aldrin Dieldrin written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Aldrin categories.

Methods To Assess Dna Damage And Repair

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Author : Robert G. Tardiff
language : en
Publisher:
Release Date : 1994-08-16

Methods To Assess Dna Damage And Repair written by Robert G. Tardiff and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-08-16 with Medical categories.

Integrates data obtained from a variety of disciplines to evaluate the current state of knowledge regarding defense mechanisms and applies this information to estimate health risks to humans exposed to substances that alter genetic material. Recognized experts document, to a large extent, which carcinogens can cause injury to human beings and their surroundings, providing guidance for the structured acquisition of key information to reduce cancer risks throughout the environment.

Toxicological Profile For 1 2 Dichloroethene

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Author :
language : en
Publisher:
Release Date : 1996

Toxicological Profile For 1 2 Dichloroethene written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Dichloroethylene categories.