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Genomic Perl


Genomic Perl
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Genomic Perl


Genomic Perl
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Author : Rex A. Dwyer
language : en
Publisher: Cambridge University Press
Release Date : 2003

Genomic Perl written by Rex A. Dwyer and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Computers categories.


This introduction to computational molecular biology will help programmers and biologists learn the skills needed to start work in this important, expanding field. The author explains many of the basic computational problems and gives concise, working programs to solve them in the Perl programming language. With minimal prerequisites, the author explains the biological background for each problem, develops a model for the solution, then introduces the Perl concepts needed to implement the solution. The book covers pairwise and multiple sequence alignment, fast database searches for homologous sequences, protein motif identification, genome rearrangement, physical mapping, phylogeny reconstruction, satellite identification, sequence assembly, gene finding, and RNA secondary structure. The concrete examples and step-by-step approach make it easy to grasp the computational and statistical methods, including dynamic programming, branch-and-bound optimization, greedy methods, maximum likelihood methods, substitution matrices, BLAST searching, and Karlin-Altschul statistics. Perl code is provided on the accompanying CD.



Genomics And Bioinformatics


Genomics And Bioinformatics
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Author : Tore Samuelsson
language : en
Publisher: Cambridge University Press
Release Date : 2012-06-07

Genomics And Bioinformatics written by Tore Samuelsson and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-07 with Computers categories.


A hands-on introduction to Unix, Perl and other bioinformatics tools using relevant and interesting molecular biology problems.



Genomics Data Analysis For Crop Improvement


Genomics Data Analysis For Crop Improvement
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Author : Priyanka Anjoy
language : en
Publisher: Springer Nature
Release Date : 2024-01-09

Genomics Data Analysis For Crop Improvement written by Priyanka Anjoy and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-09 with Technology & Engineering categories.


This book addresses complex problems associated with crop improvement programs, using a wide range of programming solutions, for genomics data handling and sustainable agriculture. It describes important concepts in genomics data analysis and sequence-based mapping approaches along with references. The book contains 16 chapters on recent developments in several methods of genomic data analysis for crop improvements and sustainable agriculture, all authored by eminent researchers who are experts in their fields. These chapters focus on applications of a wide range of key bioinformatics topics, including assembly, annotation, and visualization of next-generation sequencing (NGS) data; expression profiles of coding and noncoding RNA; statistical and quantitative genetics; trait-based association analysis, quantitative trait loci (QTL) mapping, and artificial intelligence in genomic studies. Real examples and case studies in the book will come in handy when applying the techniques. The relative scarcity of reference materials covering bioinformatics applications as compared with the readily available books also enhances the utility of this book. The targeted readers of the book are scientists, researchers, and bioinformaticians from genomics and advanced breeding in different areas. The book will appeal to the applied researchers engaged in crop improvements and sustainable agriculture by using bioinformatics tools, students, research project leaders, and practitioners from the various marginal disciplines and interdisciplinary research.



Analysis Of High Level Patterns In Genomic Data


Analysis Of High Level Patterns In Genomic Data
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Author : Brian Daniel O'Connor
language : en
Publisher:
Release Date : 2007

Analysis Of High Level Patterns In Genomic Data written by Brian Daniel O'Connor and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.




Bioinformatics For Geneticists


Bioinformatics For Geneticists
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Author : Michael R. Barnes
language : en
Publisher: John Wiley & Sons
Release Date : 2007-04-16

Bioinformatics For Geneticists written by Michael R. Barnes and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-16 with Science categories.


Praise from the reviews: "Without reservation, I endorse this text as the best resource I've encountered that neatly introduces and summarizes many points I've learned through years of experience. The gems of truth found in this book will serve well those who wish to apply bioinformatics in their daily work, as well as help them advise others in this capacity." CIRCGENETICS "This book may really help to get geneticists and bioinformaticians on 'speaking-terms'... contains some essential reading for almost any person working in the field of molecular genetics." EUROPEAN JOURNAL OF HUMAN GENETICS "... an excellent resource... this book should ensure that any researcher's skill base is maintained." GENETICAL RESEARCH “... one of the best available and most accessible texts on bioinformatics and genetics in the postgenome age... The writing is clear, with succinct subsections within each chapter....Without reservation, I endorse this text as the best resource I’ve encountered that neatly introduces and summarizes many points I’ve learned through years of experience. The gems of truth found in this book will serve well those who wish to apply bioinformatics in their daily work, as well as help them advise others in this capacity.” CIRCULATION: CARDIOVASCULAR GENETICS A fully revised version of the successful First Edition, this one-stop reference book enables all geneticists to improve the efficiency of their research. The study of human genetics is moving into a challenging new era. New technologies and data resources such as the HapMap are enabling genome-wide studies, which could potentially identify most common genetic determinants of human health, disease and drug response. With these tremendous new data resources at hand, more than ever care is required in their use. Faced with the sheer volume of genetics and genomic data, bioinformatics is essential to avoid drowning true signal in noise. Considering these challenges, Bioinformatics for Geneticists, Second Edition works at multiple levels: firstly, for the occasional user who simply wants to extract or analyse specific data; secondly, at the level of the advanced user providing explanations of how and why a tool works and how it can be used to greatest effect. Finally experts from fields allied to genetics give insight into the best genomics tools and data to enhance a genetic experiment. Hallmark Features of the Second Edition: Illustrates the value of bioinformatics as a constantly evolving avenue into novel approaches to study genetics The only book specifically addressing the bioinformatics needs of geneticists More than 50% of chapters are completely new contributions Dramatically revised content in core areas of gene and genomic characterisation, pathway analysis, SNP functional analysis and statistical genetics Focused on freely available tools and web-based approaches to bioinformatics analysis, suitable for novices and experienced researchers alike Bioinformatics for Geneticists, Second Edition describes the key bioinformatics and genetic analysis processes that are needed to identify human genetic determinants. The book is based upon the combined practical experience of domain experts from academic and industrial research environments and is of interest to a broad audience, including students, researchers and clinicians working in the human genetics domain.



Post Transcriptional Gene Regulation


Post Transcriptional Gene Regulation
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Author : Jeffrey Wilusz
language : en
Publisher: Springer Science & Business Media
Release Date : 2008

Post Transcriptional Gene Regulation written by Jeffrey Wilusz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Business & Economics categories.


Step-by-step instructions that ensure successful results.



Genome Research


Genome Research
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Author :
language : en
Publisher:
Release Date : 2004

Genome Research written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with DNA polymerases categories.




Plant Small Rna In Food Crops


Plant Small Rna In Food Crops
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Author : Praveen Guleria
language : en
Publisher: Elsevier
Release Date : 2023-04-14

Plant Small Rna In Food Crops written by Praveen Guleria and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-14 with Technology & Engineering categories.


Plant Small RNA for Food Crops provides foundational insights into the role of small RNA in food crops in varying environmental conditions and how it can help in developing molecular frameworks to support agricultural sustainability to feed the world's population. Small RNA populations have been widely identified in various plants and have been reported to be involved in regulating the molecular functioning of plants and their responses for biotic and abiotic environmental factors. Until now, however, a detailed compilation of role of small RNAs in food crops growth, yield and environmental responses had been unavailable. This book provides a detailed description of role of various small RNAs whose utilization in a range of food crops may serve to improve sustainability, productivity, and maintenance during environmental stress conditions. It brings together the reported small RNAs along with their applications specific to food crops, but also covers recent studies, innovations and future perspectives. - Provides identification and characterization of small RNA in a variety of food crops - Emphasizes molecular mechanisms affected by small RNA and their application in supporting growth, survival and productivity - Presents a comprehensive view of small RNA mediated genomics, metabolomics, proteomics and physiology of food crops



Pharmacogenomics An Introduction And Clinical Perspective


Pharmacogenomics An Introduction And Clinical Perspective
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Author : Joseph S. Bertino
language : en
Publisher: McGraw Hill Professional
Release Date : 2013

Pharmacogenomics An Introduction And Clinical Perspective written by Joseph S. Bertino and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Medical categories.


Pharmacogenomics is comprehensive textbook detailing how genetic makeup affects a body's response to drugs.



Unraveling The Biology Genetics And Host Environmental Interactions Of Acinetobacter


Unraveling The Biology Genetics And Host Environmental Interactions Of Acinetobacter
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Author : Maria Alejandra Mussi
language : en
Publisher: Frontiers Media SA
Release Date : 2020-08-19

Unraveling The Biology Genetics And Host Environmental Interactions Of Acinetobacter written by Maria Alejandra Mussi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-19 with categories.


Despite not being a disease in and of itself, antibiotic resistance could be considered the global epidemic of modern times, since it produces the failure to prevent and treat many infectious diseases. This can ultimately lead to untreatable microbial infections becoming more widespread and this will significantly increase morbidity and mortality. This worldwide problem is estimated to cause millions of deaths per year and could become an even more significant menace to humanity than established illnesses, such as cancer. In February 2017, the World Health Organization (WHO) published a list of antibiotic-resistant “priority pathogens” – a catalogue of 12 families of bacteria which pose the greatest threat to human health - and Acinetobacter baumannii is leading the list. The most critical group includes multidrug-resistant bacteria, which pose a particular threat in hospitals, nursing homes, and among patients whose care requires devices such as ventilators and blood catheters. This group includes Acinetobacter, Pseudomonas, and various Enterobacteriaceae and they are often associated with deadly infections, such as bloodstream infections and pneumonia. Furthermore, these bacteria have become resistant to a large number of antibiotics, including carbapenems and third generation cephalosporins – the best available antibiotics for treating multidrug-resistant bacteria. A. baumannii is a particularly worrisome example and demands attention: This pathogen turned into a menace to humans during the late 70s, likely as a result of intense antibiotic use in hospital settings, and became one of the microorganisms that are challenging the antibiotic era. Its extreme genome plasticity, combined with mechanisms of horizontal genetic transfer, have played a key role in the evolution of this microorganism, as well as its adaptability to unfavorable environments. However, its pathophysiology, as well as the mechanisms leading to its success as a pathogen, are not that simple to unveil. However, what is clear is that the triad of host-pathogen-environment is crucial in selection and establishment of multidrug-resistant clones and outbreaks. Indeed, there are still many aspects of this pathogen that require a deeper understanding - not only regarding mechanisms of resistance but also its global pathophysiology. For example, basic understanding of transmission mechanisms; knowledge of ‘external’ factors modulating persistence of the pathogen; genetic effects on host susceptibility and infectiousness; mechanisms of pathogenicity and their dynamics; and genetic variation of the pathogen affecting virulence and transmissibility are some aspects that would require further study. Furthermore, the importance of other members of the genus as important nosocomial pathogens, such as Acinetobacter nosocomialis, has been increasingly recognized during the last few years.