Genes In Development
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The Concept Of The Gene In Development And Evolution
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Author : Peter J. Beurton
language : en
Publisher: Cambridge University Press
Release Date : 2000-05-29
The Concept Of The Gene In Development And Evolution written by Peter J. Beurton and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-05-29 with Philosophy categories.
Advances in molecular biological research in the latter half of the twentieth century have made the story of the gene vastly complicated: the more we learn about genes, the less sure we are of what a gene really is. Knowledge about the structure and functioning of genes abounds, but the gene has also become curiously intangible. This collection of essays renews the question: what are genes? Philosophers, historians and working scientists re-evaluate the question in this volume, treating the gene as a focal point of interdisciplinary and international research. It will be of interest to professionals and students in the philosophy and history of science, genetics and molecular biology.
Maternal Effect Genes In Development
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Author :
language : en
Publisher: Academic Press
Release Date : 2020-06-24
Maternal Effect Genes In Development written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-24 with Science categories.
Current Topics in Developmental Biology series highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by one or more members of an international board of authors. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Current Topics in Developmental Biology series - Includes the latest information on maternal effect genes in development
Master Control Genes In Development And Evolution
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Author : Walter J. Gehring
language : en
Publisher: Yale University Press
Release Date : 1998-01-01
Master Control Genes In Development And Evolution written by Walter J. Gehring and has been published by Yale University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-01-01 with Science categories.
In this fascinating book, one of the world's most eminent developmental biologists discusses some of the exciting new insights into how genes control development. Walter Gehring describes in vivid detail his essential contributions to the landmark discovery of the homeobox, a characteristic DNA segment found in the genes of all higher organisms from the fruitfly to humans, and he explains how this has provided the key to our modern understanding of development and evolution. The book thus becomes not only a lucid discussion of genetics but also an engaging description of the art of scientific investigation. Gehring begins his story by looking at the work of the many researchers who laid the foundation for the fields of molecular, cellular, and developmental biology, providing insightful vignettes of past and present investigators. He then describes his laboratory's hunt for the gene that caused odd mutations in the fruitfly--in which, for example, antennae on the head were transformed into legs. He explains that researchers eventually found that the same master control genes that dictate the body plan in flies also pattern human bodies, limbs, hands, heart, and brain. And he illustrates the universality of the genetic control of development by describing the development of the eye; eyes as different as those of humans, squids, and flies, he shows, develop under the same master control gene.
Genes Development And Cancer
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Author : Howard D. Lipshitz
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Genes Development And Cancer written by Howard D. Lipshitz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
- For the first time, Nobel Prize winner, Edward B. Lewis' research papers are published within one volume - Papers are organized into sections that reflect the focus of the research - Commentaries by Howard Lipshitz highlight key methods and results by explaining the science so it is accessible to upper-level undergraduates, graduate students, and professional researchers
Genes In Development
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Author : Eva M. Neumann-Held
language : en
Publisher: Duke University Press Books
Release Date : 2006
Genes In Development written by Eva M. Neumann-Held and has been published by Duke University Press Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical categories.
In light of scientific advances such as genomics, predictive diagnostics, genetically engineered agriculture, nuclear transfer cloning, and the manipulation of stem cells, the idea that genes carry predetermined molecular programs or blueprints is pervasive. Yet new scientific discoveries—such as rna transcripts of single genes that can lead to the production of different compounds from the same pieces of dna—challenge the concept of the gene alone as the dominant factor in biological development. Increasingly aware of the tension between certain empirical results and interpretations of those results based on the orthodox view of genetic determinism, a growing number of scientists urge a rethinking of what a gene is and how it works. In this collection, a group of internationally renowned scientists present some prominent alternative approaches to understanding the role of dna in the construction and function of biological organisms. Contributors discuss alternatives to the programmatic view of dna, including the developmental systems approach, methodical culturalism, the molecular process concept of the gene, the hermeneutic theory of description, and process structuralist biology. None of the approaches cast doubt on the notion that dna is tremendously important to biological life on earth; rather, contributors examine different ideas of how dna should be represented, evaluated, and explained. Just as ideas about genetic codes have reached far beyond the realm of science, the reconceptualizations of genetic theory in this volume have broad implications for ethics, philosophy, and the social sciences. Contributors. Thomas Bürglin, Brian C. Goodwin, James Griesemer, Paul Griffiths, Jesper Hoffmeyer, Evelyn Fox Keller, Gerd B. Müller, Eva M. Neumann-Held, Stuart A. Newman, Susan Oyama, Christoph Rehmann-Sutter, Sahotra Sarkar, Jackie Leach Scully, Gerry Webster, Ulrich Wolf
T Box Genes In Development And Disease
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Author :
language : en
Publisher: Academic Press
Release Date : 2017-01-05
T Box Genes In Development And Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-05 with Science categories.
T-box Genes in Development and Disease looks at the genes encoding the T-box family of transcription factors function as key regulators of many important decision processes during embryonic and tissue development. The importance of these genes is further underlined by the fact that most members of this gene family have been conserved during evolution from worms to humans. This book brings together the current information on conserved aspects with the evolutionary innovations of the functions of these genes during developmental regulation in various animal species and then discusses their important roles in human disease.
Development
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Author : V.E.A. Russo
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Development written by V.E.A. Russo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Studies of selected model organisms have led to a greatly improved understanding not only of the molecular events which take place during development under the control of specific sets of genes, but also of epigenetic and environmental influences on these processes. This book gives an overview of all three of these levels and their relative importance, and as such will give the reader a clear picture of one of the most exciting areas of current biological research.
Coming To Life
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Author : Volhard Christiane Nusslein
language : en
Publisher: Kales Press
Release Date : 2006-04-11
Coming To Life written by Volhard Christiane Nusslein and has been published by Kales Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-11 with History categories.
Christiane Nusslein-Volhard, winner of The Nobel Prize in Medicine, gives a concise and illustrative overview of genetics, evolution, and cellular processes as well as a discussing of current ethical issues in human biology. Coming to Life is a remarkable journey through developmental biology that reveals miraculous processes in the microscopic world of cells. Through an accounting of groundbreaking discoveries, Christiane Nusslein-Volhard tells us many answers to historical and contemporary questions in science. For example, she brings us the newest knowledge about embryonic forms, explains the genetic mechanisms that influence adult development of all animals, and shares insights into the ethical standards society moist uphold in the face of new scientific discoveries. As the author leads us from laboratory research to its applications in human beings, we also come to understand why children look like their parents, how an embryonic cell knows to become an eye rather than an eyelash, and other incredible influences hat result in variety in life. Complete with her own hand-drawn illustrations, Coming to Life gives a rare opportunity to understand a Nobel Prize-winner's passion for science in concise, understandable language. 55 b/w illustrations.
Genetic Analysis Of Animal Development
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Author : Adam S. Wilkins
language : en
Publisher: Wiley-Liss
Release Date : 1993
Genetic Analysis Of Animal Development written by Adam S. Wilkins and has been published by Wiley-Liss this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Science categories.
Updated and expanded to address the latest trends in developmental genetics by examining the developmental biology of three model animal systems with a vast range of complexity and phylogenetic distance--the nematode, fruitfly and mouse. This edition places greater emphasis on molecular approaches to pattern and development formation; introduces key issues and questions involving developmental biology; explores the final stages of patterning.
Gene Interactions In Development
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Author : L. I. Korochkin
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Gene Interactions In Development written by L. I. Korochkin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Since the Russian edition of this book was published in 1975 many new research works have appeared which have made necessary some additions for the English edition, to reflect progress in molecular developmental genetics. Recent important findings in this field have brought about essential corrections to the concept of genetic regulation of the process of cell differentiation. The discovery of the mosaic structure of a gene prompted the re evaluation of our considerations about the regulation of gene activity in eukaryotes, and the data about transcriptional events during ontogenesis are of great importance as well. Formerly it was generally accepted that a derepression of genes was responsible for cell differentiation in the process of develop ment. Recently three important conclusions have been derived (Davidson and Britten, 1979) which help to pose the problem in a new way: 1) Only a small part of single copy sequences of DNA is represented in nuclear RNA of a given type of cell or tissue: 10% to 20% in sea urchin embryos, 11 % in rat liver, 4% to 6% in Drosophila cell culture, etc. Since only about 10% of single copy sequences represent the structural genes (Davidson and Britten, 1973), transcription of almost the whole set of structural genes occurs.