Diagnostic Molecular Pathology
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Diagnostic Molecular Pathology
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Author : William B. Coleman
language : en
Publisher: Academic Press
Release Date : 2016-10-05
Diagnostic Molecular Pathology written by William B. Coleman and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-05 with Science categories.
Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing is organized around disease types (genetic disease, infectious disease, neoplastic disease, among others). In each section, the authors provide background on disease mechanisms and describe how laboratory testing is built on knowledge of these mechanisms. Sections are dedicated to general methodologies employed in testing (to convey the concepts reflected in the methods), and specific description of how these methods can be applied and are applied to specific diseases are described. The book does not present molecular methods in isolation, but considers how other evidence (symptoms, radiology or other imaging, or other clinical tests) is used to guide the selection of molecular tests or how these other data are used in conjunction with molecular tests to make diagnoses (or otherwise contribute to clinical workup). In addition, final chapters look to the future (new technologies, new approaches) of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests. Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing contains exercises to test readers on their understanding of how molecular diagnostic tests are utilized and the value of the information that can be obtained in the context of the patient workup. Readers are directed to an ancillary website that contains supplementary materials in the form of exercises where decision trees can be employed to simulate actual clinical decisions. - Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis, and classification in the clinical workup of a patient - Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for prognostication of disease - Features an ancillary website with self-testing exercises where decision trees can be employed to simulate actual clinical decisions - Highlights new technologies and approaches of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests
Cell And Tissue Based Molecular Pathology E Book
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Author : Raymond R. Tubbs
language : en
Publisher: Elsevier Health Sciences
Release Date : 2008-09-22
Cell And Tissue Based Molecular Pathology E Book written by Raymond R. Tubbs and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-22 with Medical categories.
This volume in the Foundations in Diagnostic Pathology Series packs today's most essential cell and tissue base molecular pathology into a compact, high-yield format! It focuses on the state of the art in practical validated molecular diagnostics as applied across the fields of surgical pathology and cytology. With an emphasis on current, clinically valid, and diagnostically important applications today and in the near future, you can be assured you’re getting the most up-to-date, authoritative coverage available. Its pragmatic, well-organized approach, nearly 250 full-color illustrations, and at-a-glance boxes and tables make the information you need easy to access. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice! Offers detailed discussions on today’s technologies to help you select the best test for case evaluation. Presents recognized molecular pathologists who convey the most current information, keeping you on the cusp of your field. Features nearly 250 full-color illustrations that present important pathologic features, enabling you to form a differential diagnosis and compare your findings with actual cases. Uses a consistent, user-friendly format, including at-a-glance boxes and tables for easy reference.
Diagnostic Pathology Molecular Oncology E Book
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Author : Mohammad A. Vasef
language : en
Publisher: Elsevier Health Sciences
Release Date : 2016-03-23
Diagnostic Pathology Molecular Oncology E Book written by Mohammad A. Vasef and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-23 with Medical categories.
This volume in the highly regarded Diagnostic Pathology series provides a clearer understanding of molecular pathology as it relates to the transformation and pathogenesis of cancer. Diagnostic Pathology: Molecular Oncology is the first reference to apply a practical and clinical approach to examining how molecular mutations affect common medical diseases. Additionally, it identifies the relevant and appropriate molecular tests to perform for a complete work-up in the era of molecular-targeted therapies. Easy to use and packed with outstanding illustrations, this is an essential resource for all pathologists or clinicians who need to keep up with the ever-evolving field of molecular medicine. Up-to-date information on a variety of topics Next-generation sequencing for determining gene mutations Diagnostic use of soft tissue mutations Use of solid tissue mutations such as EGFR, BRAF, and KRAS for diagnosis and treatment of different carcinomas and melanoma Interpreting newly found mutations in hematopathology such as MYD88 mutations Understanding bioinformatics Guidance on selecting the right test(s) at the right time for the right patient Comparisons of molecular testing methods (i.e., FISH testing vs. cytogenetics) More than 2,000 images including H&E stains, immunostains, and FISH images
Diagnostic Molecular Pathology In Practice
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Author : Iris Schrijver
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-09-09
Diagnostic Molecular Pathology In Practice written by Iris Schrijver and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-09 with Medical categories.
This entirely case-based book covers a broad cross-section of the practical issues frequently encountered in the day-to-day activities of a molecular genetic pathologist. The book is divided into four sections on the principal areas addressed in molecular genetic pathology (MGP): inherited diseases, hematopathology, solid tumors, and infectious diseases. The topics covered by the cases in each section include test selection, qualitative and quantitative laboratory techniques, test interpretation, prognostic and therapeutic considerations, ethical considerations, technical troubleshooting, and result reporting. This book will be ideal for trainees in MGP and clinical molecular genetics who require a practice-based preparation for board examinations. It will also be very useful for residents and fellows in medical specialties to which MGP is pertinent, and for practicing pathologists who want to learn more about the current practice of molecular diagnostics.
Basic Concepts Of Molecular Pathology
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Author : Philip T. Cagle
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-06-10
Basic Concepts Of Molecular Pathology written by Philip T. Cagle and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-10 with Medical categories.
Over the past two decades there has been an explosion in knowledge about the molecular pathology of human diseases which accelerated with the sequencing of the human genome in 2003. Molecular diagnostics and molecular targeted therapy have contributed to the current concept of personalized patient care that is now routine in many medical centers. As a result, general and subspecialty pathologists, clinical practitioners of all types and radiologists must now have an understanding of the basic concepts of molecular pathology and their role in new diagnostic and therapeutic applications to patient care. The Molecular Pathology Library series was created to bridge the gap between traditional basic science textbooks in molecular biology and traditional medical textbooks for organ-specific diseases. Basic Concepts of Molecular Pathology is designed as a stand-alone book to provide the pathologist, clinician or radiologist with a concise review of the essential terminology, concepts and tools of molecular biology that are applied to the understanding, diagnosis and treatment of human diseases in the age of personalized medicine. Those medical practitioners, residents, fellows and students who need to refer to the terminology and concepts of molecular pathology in their patient care will find the Basic Concepts of Molecular Pathology to be a succinct, portable, user-friendly aid in their practice and studies. The service-based physician will find this handy reference to be valuable at the laboratory benchside, at the patient bedside, at multidisciplinary patient care conferences or as a review for examinations.
Molecular Pathology In Clinical Practice
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Author : Debra G.B. Leonard
language : en
Publisher: Springer
Release Date : 2016-02-02
Molecular Pathology In Clinical Practice written by Debra G.B. Leonard and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-02 with Medical categories.
This authoritative textbook offers in-depth coverage of all aspects of molecular pathology practice and embodies the current standard in molecular testing. Since the successful first edition, new sections have been added on pharmacogenetics and genomics, while other sections have been revised and updated to reflect the rapid advances in the field. The result is a superb reference that encompasses molecular biology basics, genetics, inherited cancers, solid tumors, neoplastic hematopathology, infectious diseases, identity testing, HLA typing, laboratory management, genomics and proteomics. Throughout the text, emphasis is placed on the molecular variations being detected, the clinical usefulness of the tests and important clinical and laboratory issues. The second edition of Molecular Pathology in Clinical Practice will be an invaluable source of information for all practicing molecular pathologists and will also be of utility for other pathologists, clinical colleagues and trainees.
Diagnostic Molecular Pathology
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Author :
language : en
Publisher:
Release Date : 2000
Diagnostic Molecular Pathology written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Diagnosis, Laboratory categories.
Diagnostic Molecular Pathology
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Author : C. S. Herrington
language : en
Publisher:
Release Date : 1993
Diagnostic Molecular Pathology written by C. S. Herrington and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with categories.
Molecular Pathology And Diagnostics Of Cancer
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Author : Domenico Coppola
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-29
Molecular Pathology And Diagnostics Of Cancer written by Domenico Coppola and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-29 with Medical categories.
Molecular pathology is based on the emergence of new techniques that greatly enhance the diagnostic accuracy when facing with challenging differential diagnoses. In addition, new molecular techniques are entering the clinical arena for their value in predicting therapy response and tumor prognosis. This book provides a guide for the practicing pathologist and for both pathology residents and fellows during the daily sign-out of challenging cases. The book is organized by anatomical systems and provides a detailed description of molecular tests that may help in the diagnosis. Furthermore, a description of the current molecular tests required to identify patients for treatment is offered. The application of molecular pathology techniques to the clinical practice has already shown its usefulness and the number of such tests is growing exponentially as more molecular targets are discovered. Molecular Pathology and Diagnostics of Cancer will give practicing and training pathologists an up-to date resource to guide the correct management of pathology cases requiring molecular testing.
Molecular Testing In Cancer
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Author : George M. Yousef
language : en
Publisher: Springer Science & Business
Release Date : 2014-04-21
Molecular Testing In Cancer written by George M. Yousef and has been published by Springer Science & Business this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-21 with Medical categories.
Molecular Testing in Cancer provides a state of the art review of clinically relevant molecular pathology in cancer. The book provides a brief, easy to read review of commonly employed diagnostic molecular techniques including recently developed "next generation" analytic tools, and offers a system-based run-through of the utility of molecular testing in individual cancer types, as well as reviewing current markers in cancer diagnosis, prognosis, and management. The volume also provides a prospective for the future which includes recently characterized and emerging biomarkers. Written by experts in the field, Molecular Testing in Cancer serves as a useful and comprehensive resource for pathologists, hematologists, laboratory technicians and molecular scientists.