Cns Neuroprotection
DOWNLOAD
Download Cns Neuroprotection PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Cns Neuroprotection book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Cns Neuroprotection
DOWNLOAD
Author : Frank W. Marcoux
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Cns Neuroprotection written by Frank W. Marcoux and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
"CNS neuroprotection" was a common subject of papers, symposia, and reviews during the previous "decade of the brain. " Indeed, in recent years, experimental study of putative neuroprotective agents prompted clinical trials of numerous drug candidates in acute and chronic human neurodegenerative conditions. While the outcomes of these trials have not been as successful as initially hoped, these were early explorations, and the pipeline of relevant ideas continues to grow in strength and depth. We predict that early in this new millennium, crippling disorders such as stroke and Alzheimer's disease will be treated effectively by therapeutic neuroprotective strategies. This volume of the Handbook of Experimental Pharmacology titled eNS Neuroprotection provides a pharmacological perspective on currently promis ing neuroprotective approaches, and a clinical perspective on the challenges involved in establishing the efficacy of these approaches through appropriate clinical trials. Section I, "Mechanistic Approaches to CNS Neuroprotection," reviews major injury mechanisms that have formed the basis for many past and present clinical trials conducted around the world. Dr. KIM and colleagues, Washington University School of Medicine, review the status of blocking excitotoxicity as an approach to CNS neuroprotection. Dr. WANG, Pfizer Global Research and Development,Ann Arbor Laboratories, outlines evidence supporting a contri bution of apoptosis to pathological neuronal or glial cell loss. Drs. BECKER and HALLENBECK, University of Washington and the National Institute on Neuro logical Diseases and Stroke, respectively, argue that inhibiting inflammatory pathways in the brain can be neuroprotective. Dr.
Cns Neuroprotection
DOWNLOAD
Author : M. Flint Beal
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-07-10
Cns Neuroprotection written by M. Flint Beal and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-07-10 with Medical categories.
With contributions by numerous experts
Cns Neuroprotection
DOWNLOAD
Author : Frank W Marcoux
language : en
Publisher: Springer
Release Date : 2014-01-15
Cns Neuroprotection written by Frank W Marcoux and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-15 with categories.
Neuroprotection
DOWNLOAD
Author : Thomas J. J. Blanck
language : en
Publisher:
Release Date : 1997
Neuroprotection written by Thomas J. J. Blanck and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Medical categories.
his latest Society of Cardiovascular Anesthesiologists monograph brings readers up-to-date on protecting patients from neurological problems while undergoing cardiovascular surgery
Molecular And Cellular Biology Of Neuroprotection In The Cns
DOWNLOAD
Author : Christian Alzheimer
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Molecular And Cellular Biology Of Neuroprotection In The Cns written by Christian Alzheimer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Given the very limited capacity of regeneration in the brain, protecting neurons that are on the brink of death is a major challenge for basic and clinical neuroscience, with implications for a broad spectrum of acute and chronic neurological and psychiatric diseases. This book brings together leading experts from neurobiology, neurophysiology, neuropharmacology, neuroimmunology and clinical neuroscience to highlight the most recent milestones in this rapidly evolving field. The book will serve as a reference for both basic neuroscientists and clinicians interested in an authoritative update on the molecular and cellular biology of neuroprotection and its promises for new therapeutic strategies.
Neuroprotection
DOWNLOAD
Author : Mathias Bähr
language : en
Publisher: Wiley-Blackwell
Release Date : 2004-09-13
Neuroprotection written by Mathias Bähr and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-09-13 with Medical categories.
In this first book to cover model systems, molecular mechanisms and clinical trials all in one volume internationally renowned scientists and clinicians provide a comprehensive treatment of neuroprotective strategies for all important neurological disorders. Following an overview of neurodegenerative, traumatic, and ischemic disorders, the book goes on to cover in vitro and animal model systems as well as cellular and molecular mechanisms. An extremely helpful analysis of clinical studies explains reasons for their success and failure, and the whole is rounded off with a look at the current challenges and hopes for the development of effective treatment strategies in the future.
Innate Tolerance In The Cns
DOWNLOAD
Author : Jeffrey M. Gidday
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-09-21
Innate Tolerance In The Cns written by Jeffrey M. Gidday and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-21 with Science categories.
Cerebral preconditioning is a phenomenon wherein a mild insult or stress induces cellular and tissue adaptation or tolerance to a later, severe injury, therefore reflecting the efficacy of endogenous mechanisms of cerebrovascular protection. Initially identified for rapid cardiac protection, preconditioning has expanded to all aspects of CNS protection from ischemia, trauma and potentially neurodegeneration. Many different stimuli or stressors have been identified as preconditioning agents, suggesting a downstream convergence of mechanisms and underscoring the potential for translational application of preconditioning in the clinic. Moreover, the fundamental mechanisms responsible for preconditioning-induced tolerance will help in the design novel pharmacological approaches for neuroprotection. While stroke and many other brain injuries are not predictable, in some populations (e.g., metabolic syndrome, patients undergoing carotid endarterectomy, aneurysm clipping, or with recent TIAs) the risk for stroke is identifiable and significant, and preconditioning may represent a useful strategy for neuroprotection. For unpredictable injuries, post-conditioning the brain – or inducing endogenous protective mechanisms after the initial injury – can also abrogate the extent of injury. Finally, remote pre- and post-conditioning methods have been developed in animals, and are now being tested in clinical trials, wherein a brief, noninjurious stress to a noncerebral tissue (i.e., skeletal muscle) can provide protection to the CNS and thereby allows clinicians the opportunity to circumvent concerns regarding the direct preconditioning of neurological tissues.
New Perspectives Of Central Nervous System Injury And Neuroprotection
DOWNLOAD
Author : Hari Shanker Sharma
language : en
Publisher: Academic Press
Release Date : 2012-07-10
New Perspectives Of Central Nervous System Injury And Neuroprotection written by Hari Shanker Sharma and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-10 with Medical categories.
Annotation Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia. Reviews written by experts in such a way thatprovides basic knowledge for beginners and advanced information for researchers and experts. New aspects of Neurodegenerative diseasessuch as;Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis are presented with thelatest therapeutic measures. Exacerbation of brain pathology in hypertension or diabetes is discussed for the first time.
Neurotrauma And Critical Care Of The Spine
DOWNLOAD
Author : Jack Jallo
language : en
Publisher: Thieme
Release Date : 2018-03-21
Neurotrauma And Critical Care Of The Spine written by Jack Jallo and has been published by Thieme this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-21 with Medical categories.
"This book is the most useful summary of present knowledge about epidemiology, pathophysiology, assessment and management of spinal cord injuries today. It is a great book that deserves a widespread distribution among spine surgeons and physicians involved in the treatment of spinal injuries." - European Journal of Orthopaedic Surgery & Traumatology Neurotrauma and Critical Care of the Spine, 2nd edition, by a distinguished critical care neurosurgeon, Jack Jallo, and a renowned spine surgeon, Alexander Vaccaro, incorporates salient components of the highly praised first edition. The updated text reflects cutting-edge discussion on spine injury management in a neurocritical care setting. Contributions from top experts in neurosurgery, orthopaedic surgery, neurology, critical care, cardiac and pulmonary care, and trauma surgery infuse this book with a well-rounded perspective. From the pre-hospital to intensive care setting, this unique reference provides a comprehensive, yet concise approach to the treatment of acute spinal cord injury and management of patients with chronic SCI. Chapters new to this edition include neurological assessment of spinal injury, clearing the cervical spine, management of concurrent TBI and spinal injury, blood pressure and oxygen management, temperature management, fluids and osmotherapy, pharmacology, autonomic dysreflexia, infection after SCI, and emerging therapies. Key Highlights, Evaluation and management of SCI in the athlete including different injury syndromes and the latest recommendations for "return to play" in less severe cases Management of pediatric spinal injuries in the NICU with illustrative cases Specialized topics include a comprehensive review of SCI pharmacology, recent medical advances, socioeconomic and quality-of-life considerations Nearly 100 high quality illustrations facilitate understanding of complex anatomy and techniques Summary tables provide a handy overview of injury type, causes, characteristics, and recommended imaging modalities The definitive guide on the management of cervical, cervicothoracic, and thoracolumbar injuries, this is essential reading for neurosurgeons, orthopaedic surgeons, trauma and emergency specialists, and residents in these specialties. Paired with Neurotrauma and Critical Care of the Brain, 2nd edition, this dynamic duo is the most up-to-date neurocritical care reference available today.
Xvith International Symposium On Cerebral Blood Flow And Metabolism
DOWNLOAD
Author : Kyuya Kogure
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 1993
Xvith International Symposium On Cerebral Blood Flow And Metabolism written by Kyuya Kogure and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medical categories.