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Analyzing Microarray Gene Expression Data


Analyzing Microarray Gene Expression Data
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Analyzing Microarray Gene Expression Data


Analyzing Microarray Gene Expression Data
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Author : Geoffrey J. McLachlan
language : en
Publisher: John Wiley & Sons
Release Date : 2005-02-18

Analyzing Microarray Gene Expression Data written by Geoffrey J. McLachlan and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-02-18 with Mathematics categories.


A multi-discipline, hands-on guide to microarray analysis of biological processes Analyzing Microarray Gene Expression Data provides a comprehensive review of available methodologies for the analysis of data derived from the latest DNA microarray technologies. Designed for biostatisticians entering the field of microarray analysis as well as biologists seeking to more effectively analyze their own experimental data, the text features a unique interdisciplinary approach and a combined academic and practical perspective that offers readers the most complete and applied coverage of the subject matter to date. Following a basic overview of the biological and technical principles behind microarray experimentation, the text provides a look at some of the most effective tools and procedures for achieving optimum reliability and reproducibility of research results, including: An in-depth account of the detection of genes that are differentially expressed across a number of classes of tissues Extensive coverage of both cluster analysis and discriminant analysis of microarray data and the growing applications of both methodologies A model-based approach to cluster analysis, with emphasis on the use of the EMMIX-GENE procedure for the clustering of tissue samples The latest data cleaning and normalization procedures The uses of microarray expression data for providing important prognostic information on the outcome of disease



Microarray Gene Expression Data Analysis


Microarray Gene Expression Data Analysis
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Author : Helen Causton
language : en
Publisher: John Wiley & Sons
Release Date : 2009-04-01

Microarray Gene Expression Data Analysis written by Helen Causton and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-01 with Science categories.


This guide covers aspects of designing microarray experiments and analysing the data generated, including information on some of the tools that are available from non-commercial sources. Concepts and principles underpinning gene expression analysis are emphasised and wherever possible, the mathematics has been simplified. The guide is intended for use by graduates and researchers in bioinformatics and the life sciences and is also suitable for statisticians who are interested in the approaches currently used to study gene expression. Microarrays are an automated way of carrying out thousands of experiments at once, and allows scientists to obtain huge amounts of information very quickly Short, concise text on this difficult topic area Clear illustrations throughout Written by well-known teachers in the subject Provides insight into how to analyse the data produced from microarrays



Analysis Of Microarray Gene Expression Data


Analysis Of Microarray Gene Expression Data
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Author : Mei-Ling Ting Lee
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-08

Analysis Of Microarray Gene Expression Data written by Mei-Ling Ting Lee and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-08 with Science categories.


After genomic sequencing, microarray technology has emerged as a widely used platform for genomic studies in the life sciences. Microarray technology provides a systematic way to survey DNA and RNA variation. With the abundance of data produced from microarray studies, however, the ultimate impact of the studies on biology will depend heavily on data mining and statistical analysis. The contribution of this book is to provide readers with an integrated presentation of various topics on analyzing microarray data.



Advanced Analysis Of Gene Expression Microarray Data


Advanced Analysis Of Gene Expression Microarray Data
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Author : Aidong Zhang
language : en
Publisher: World Scientific
Release Date : 2006

Advanced Analysis Of Gene Expression Microarray Data written by Aidong Zhang and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Science categories.


Focuses on the development and application of the latest advanced data mining, machine learning, and visualization techniques for the identification of interesting, significant, and novel patterns in gene expression microarray data. Describes cutting-edge methods for analyzing gene expression microarray data. Coverage includes gene-based analysis, sample-based analysis, pattern-based analysis and visualization tools.



Statistical Analysis Of Gene Expression Microarray Data


Statistical Analysis Of Gene Expression Microarray Data
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Author : Terry Speed
language : en
Publisher: CRC Press
Release Date : 2003-03-26

Statistical Analysis Of Gene Expression Microarray Data written by Terry Speed and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-03-26 with Mathematics categories.


Although less than a decade old, the field of microarray data analysis is now thriving and growing at a remarkable pace. Biologists, geneticists, and computer scientists as well as statisticians all need an accessible, systematic treatment of the techniques used for analyzing the vast amounts of data generated by large-scale gene expression studies



The Analysis Of Gene Expression Data


The Analysis Of Gene Expression Data
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Author : Giovanni Parmigiani
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-11

The Analysis Of Gene Expression Data written by Giovanni Parmigiani and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-11 with Medical categories.


This book presents practical approaches for the analysis of data from gene expression micro-arrays. It describes the conceptual and methodological underpinning for a statistical tool and its implementation in software. The book includes coverage of various packages that are part of the Bioconductor project and several related R tools. The materials presented cover a range of software tools designed for varied audiences.



Dna Microarray Technology And Data Analysis In Cancer Research


Dna Microarray Technology And Data Analysis In Cancer Research
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Author : Shaoguang Li
language : en
Publisher: World Scientific
Release Date : 2009-02-04

Dna Microarray Technology And Data Analysis In Cancer Research written by Shaoguang Li and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-02-04 with Medical categories.


DNA microarray technology has become a useful technique in gene expression analysis for the development of new diagnostic tools and for the identification of disease genes and therapeutic targets for human cancers. Appropriate control for DNA microarray experiment and reliable analysis of the array data are key to performing the assay and utilizing the data correctly. The most difficult challenge has been the lack of a powerful method to analyze the data for all genes (more than 30,000 genes) simultaneously and to use the microarray data in a decision-making process. In this book, the authors describe DNA microarray technology and data analysis by pointing out current advantages and disadvantages of the technique and available analytical methods. Crucially, new ideas and analytical methods based on the authors' own experience in DNA microarray study and analysis are introduced. It is believed that this new way of interpreting and analyzing microarray data will bring us closer to success in decision-making using the information obtained through the DNA microarray technology.



Analysis Of Microarray Data


Analysis Of Microarray Data
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Author : Matthias Dehmer
language : en
Publisher: John Wiley & Sons
Release Date : 2008-09-08

Analysis Of Microarray Data written by Matthias Dehmer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-08 with Medical categories.


This book is the first to focus on the application of mathematical networks for analyzing microarray data. This method goes well beyond the standard clustering methods traditionally used. From the contents: * Understanding and Preprocessing Microarray Data * Clustering of Microarray Data * Reconstruction of the Yeast Cell Cycle by Partial Correlations of Higher Order * Bilayer Verification Algorithm * Probabilistic Boolean Networks as Models for Gene Regulation * Estimating Transcriptional Regulatory Networks by a Bayesian Network * Analysis of Therapeutic Compound Effects * Statistical Methods for Inference of Genetic Networks and Regulatory Modules * Identification of Genetic Networks by Structural Equations * Predicting Functional Modules Using Microarray and Protein Interaction Data * Integrating Results from Literature Mining and Microarray Experiments to Infer Gene Networks The book is for both, scientists using the technique as well as those developing new analysis techniques.



Analysis Of Growth Factor Signaling In Embryos


Analysis Of Growth Factor Signaling In Embryos
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Author : Malcolm Whitman
language : en
Publisher: CRC Press
Release Date : 2006-08-15

Analysis Of Growth Factor Signaling In Embryos written by Malcolm Whitman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-08-15 with Science categories.


Developmental biologists have been driven to investigate growth factor signaling in embryos in order to understand the regulatory mechanisms underlying a given developmental process. Thus, it is critical to explore the technical methods and experimental designs for growth factor signaling in embryos. Focusing on specific pathways or pathway comp



Methods Of Microarray Data Analysis V


Methods Of Microarray Data Analysis V
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Author : Patrick McConnell
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-02-24

Methods Of Microarray Data Analysis V written by Patrick McConnell and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-02-24 with Science categories.


As studies using microarray technology have evolved, so have the data analysis methods used to analyze these experiments. The CAMDA (Critical Assessment of Microarray Data Analysis) conference was the first to establish a forum for a cross section of researchers to look at a common data set and apply innovative analytical techniques to microarray data. Methods of Microarray Analysis V includes selected papers from CAMDA'04, and focuses on data sets relating to a significant global health issue, malaria. Previous books focused on classification (V. I), pattern recognition (V. II), quality control issues (V. III), and associating array data with a survival endpoint, lung cancer, (V. IV). The contributions come from research fields including statistics, biology, computer science and mathematics. Part of the book is devoted to review papers, which provide a more general look at various analytical approaches. It also presents some background readings for the advanced topics discussed in the CAMDA papers.