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Analogue Based Drug Discovery


Analogue Based Drug Discovery
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Analogue Based Drug Discovery


Analogue Based Drug Discovery
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Author : IUPAC
language : en
Publisher: John Wiley & Sons
Release Date : 2006-12-13

Analogue Based Drug Discovery written by IUPAC and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-13 with Science categories.


The first authoritative overview of past and current strategies for successful drug development by analog generation, this unique resource spans all important drug classes and all major therapeutic fields, including histamine antagonists, ACE inhibitors, beta blockers, opioids, quinolone antibiotics, steroids and anticancer platinum compounds. Of the 19 analog classes presented in detail, 9 are described by the scientists who discoverd them. The book includes a table of the most successful drug analogs as based on the IMS ranking and compares them in terms of chemical structure, mode of action and patentability.



Analogue Based Drug Discovery


Analogue Based Drug Discovery
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Author : Janos Fischer
language : en
Publisher: LibreDigital
Release Date : 2006-03-10

Analogue Based Drug Discovery written by Janos Fischer and has been published by LibreDigital this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-10 with Science categories.


The easiest way to create a new drug is to modify an existing one. These so-called drug analogs account for about half of all "new" drugs and are of tremendous importance both for medical and financial reasons. In addition, drug analogs can be modeled on naturally occurring bioactive substances that do not make good drugs on their own, thereby considerably increasing the therapeutic range of pharmaceutical medicine. This first authoritative and systematic overview of past and current strategies for successful drug development by modification spans all important drug classes and all major therapeutic fields. It discusses analog-based drug discovery for, among others, beta-blockers, ACE inhibitors, steroids, opiates, coxibs, stigmines, proton pump inhibitors, platinum compounds and quinolones. In addition, case studies on selected commercially successful drug analogs provide prime advice for new drug development projects based on modification. The book is rounded off with an exclusive table of the 1,000 most successful drug analogs according to IMS ranking, classified in terms of chemical structure, mode of action and patentability. Officially endorsed by the International Union of Pure and Applied Chemistry's Drug Development Committee, indispensable for medicinal and pharmaceutical chemists in all fields.



Analogue Based Drug Discovery


Analogue Based Drug Discovery
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Author : IUPAC
language : en
Publisher: Wiley-VCH
Release Date : 2006-03-10

Analogue Based Drug Discovery written by IUPAC and has been published by Wiley-VCH this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-10 with Science categories.


The first authoritative overview of past and current strategies for successful drug development by analog generation, this unique resource spans all important drug classes and all major therapeutic fields, including histamine antagonists, ACE inhibitors, beta blockers, opioids, quinolone antibiotics, steroids and anticancer platinum compounds. Of the 19 analog classes presented in detail, 9 are described by the scientists who discoverd them. The book includes a table of the most successful drug analogs as based on the IMS ranking and compares them in terms of chemical structure, mode of action and patentability.



Analogue Based Drug Discovery Ii


Analogue Based Drug Discovery Ii
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Author : János Fischer
language : en
Publisher: John Wiley & Sons
Release Date : 2010-08-24

Analogue Based Drug Discovery Ii written by János Fischer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-08-24 with Medical categories.


Born out of a project of the IUPAC's committee on Medicinal Chemistry and Drug Development, this reference addresses past and current strategies for successful drug analog development, extending the previously published volume by nine new analog classes and eight case studies. Like its precursor, this volume also contains a general section discussing universally applicable strategies for analog discovery and development. Spanning a wide range of therapeutic fields and chemical classes, the two volumes together constitute the first systematic approach to drug analog development. Of interest to virtually every researcher working in drug discovery and pharmaceutical chemistry.



Analogue Based Drug Discovery Iii


Analogue Based Drug Discovery Iii
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Author : J¿nos Fischer
language : en
Publisher: John Wiley & Sons
Release Date : 2013-01-29

Analogue Based Drug Discovery Iii written by J¿nos Fischer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-29 with Medical categories.


Most drugs are analogue drugs. There are no general rules how a new drug can be discovered, nevertheless, there are some observations which help to find a new drug, and also an individual story of a drug discovery can initiate and help new discoveries. Volume III is a continuation of the successful book series with new examples of established and recently introduced drugs. The major part of the book is written by key inventors either as a case study or a study of an analogue class. With its wide range across a variety of therapeutic fields and chemical classes, this is of interest to virtually every researcher in drug discovery and pharmaceutical chemistry, and -- together with the previous volumes -- constitutes the first systematic approach to drug analogue development.



Chemistry And Industry


Chemistry And Industry
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Author :
language : en
Publisher:
Release Date : 2009

Chemistry And Industry written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Chemistry, Technical categories.




European Journal Of Organic Chemistry


European Journal Of Organic Chemistry
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Author :
language : en
Publisher:
Release Date : 2007

European Journal Of Organic Chemistry written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Bioorganic chemistry categories.




Trends In Drug Research


Trends In Drug Research
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Author : V. Claassen
language : en
Publisher: Elsevier Publishing Company
Release Date : 1990

Trends In Drug Research written by V. Claassen and has been published by Elsevier Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Medical categories.


This volume comprises the invited lectures of the Seventh Noordwijkerhout-Camerino Symposium. The authors of the 28 papers give a detailed account of recent advances in the fields of receptor-drug interactions, structure-activity relationships, molecular toxicology, drug targeting, peptidergic drugs, inhibitors of cholesterol biosynthesis, antimalarial and antileprosy drugs. Containing up-to-date surveys of recent trends in synthetical and biological investigations in drug design, this volume should prove invaluable to medicinal chemists and to pharmacologists and toxicologists working in the field of drug design and development.



Thalidomide Analogues


Thalidomide Analogues
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Author : Scott Michael Capitosti
language : en
Publisher:
Release Date : 2004

Thalidomide Analogues written by Scott Michael Capitosti and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with categories.




Computational Methods In Drug Design


Computational Methods In Drug Design
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Author :
language : en
Publisher:
Release Date : 1993

Computational Methods In Drug Design written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Drugs categories.