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Acute Leukemias Iv


Acute Leukemias Iv
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Acute Leukemias Iv


Acute Leukemias Iv
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Author : T. Büchner
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Acute Leukemias Iv written by T. Büchner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


The rates of acute leukemia cure have gradually improved over the last decade. Clinical study results reflect the impact of chemotherapy intensity and duration, the role of prolonged maintenance, intensified consolidation or very early intensification. Further progress has also been achieved in bone marrow trans plantation, and recent prospective studies and meta-analyses have contributed comparisons of the high antileukemic efficacy of bone marrow transplantation to that of improved chemotherapy. This allows a more successful combining of the two forms of treatment. New prognostic factors have emerged from both cytogenetic and molecular genetic research. Thus, the Philadelphia chromosome translocation and the bcr/abl gene rearrangement have proven to be the dominating risk factor in acute lymphoblastic leukemia. Since the frequency increases with age, differences in prognosis between children and adults can be explained. Evaluation of molecular and immunologic leukemia cell markers has provided a better understanding of residual leukemia in clinical remission, as a prognostic factor and in monitoring the effectiveness of the antileukemic strategy. Recent work on leukemic cell biology has resulted in novel therapeutic approaches such as terminal differentiation by all-trans-retinoic acid, modulation of chemotherapy by hematopoietic growth factors such as GM-CSF and enhancement of immunologic control by cytokines such as interleukin 2. New antimicrobial drugs and the application of mostly empiric anti-infectious strategies have helped reducing the therapeutic risk. Thus, a number of recent achievements have provided us with new options in the management of patients with acute leukemias.



Acute Leukemias Iv


Acute Leukemias Iv
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Author : Thomas Büchner
language : en
Publisher: Springer
Release Date : 1994-02-24

Acute Leukemias Iv written by Thomas Büchner and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-02-24 with Medical categories.


The rates of acute leukemia cure have gradually improved over the last decade. Clinical study results reflect the impact of chemotherapy intensity and duration, the role of prolonged maintenance, intensified consolidation or very early intensification. Further progress has also been achieved in bone marrow trans plantation, and recent prospective studies and meta-analyses have contributed comparisons of the high antileukemic efficacy of bone marrow transplantation to that of improved chemotherapy. This allows a more successful combining of the two forms of treatment. New prognostic factors have emerged from both cytogenetic and molecular genetic research. Thus, the Philadelphia chromosome translocation and the bcr/abl gene rearrangement have proven to be the dominating risk factor in acute lymphoblastic leukemia. Since the frequency increases with age, differences in prognosis between children and adults can be explained. Evaluation of molecular and immunologic leukemia cell markers has provided a better understanding of residual leukemia in clinical remission, as a prognostic factor and in monitoring the effectiveness of the antileukemic strategy. Recent work on leukemic cell biology has resulted in novel therapeutic approaches such as terminal differentiation by all-trans-retinoic acid, modulation of chemotherapy by hematopoietic growth factors such as GM-CSF and enhancement of immunologic control by cytokines such as interleukin 2. New antimicrobial drugs and the application of mostly empiric anti-infectious strategies have helped reducing the therapeutic risk. Thus, a number of recent achievements have provided us with new options in the management of patients with acute leukemias.



Acute Leukemias


Acute Leukemias
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Author : Th Büchner
language : en
Publisher: Springer
Release Date : 1987

Acute Leukemias written by Th Büchner and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Medical categories.




Modern Trends In Human Leukemia Iv


Modern Trends In Human Leukemia Iv
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Author : Rolf Neth
language : en
Publisher: Springer
Release Date : 1981

Modern Trends In Human Leukemia Iv written by Rolf Neth and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Medical categories.




Immunological Studies In Acute Leukemia And Effect Of Immune Complexes On Blood Cells Detected By Microcalorimetry


Immunological Studies In Acute Leukemia And Effect Of Immune Complexes On Blood Cells Detected By Microcalorimetry
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Author : Roger Fäldt
language : en
Publisher:
Release Date : 1982

Immunological Studies In Acute Leukemia And Effect Of Immune Complexes On Blood Cells Detected By Microcalorimetry written by Roger Fäldt and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Immune complexes categories.




Workshop On Prognostic Factors In Human Acute Leukemia


Workshop On Prognostic Factors In Human Acute Leukemia
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Author : Theodor M. Fliedner
language : en
Publisher: Pergamon
Release Date : 1975

Workshop On Prognostic Factors In Human Acute Leukemia written by Theodor M. Fliedner and has been published by Pergamon this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Science categories.




Clinical And Pharmacological Studies On Cytosine Arabinoside In Acute Leukemia


Clinical And Pharmacological Studies On Cytosine Arabinoside In Acute Leukemia
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Author : Aleida Maria Schonk
language : en
Publisher:
Release Date : 1982*

Clinical And Pharmacological Studies On Cytosine Arabinoside In Acute Leukemia written by Aleida Maria Schonk and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982* with categories.




The Journal Of The Association Of Physicians Of India


The Journal Of The Association Of Physicians Of India
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Author :
language : en
Publisher:
Release Date : 1995

The Journal Of The Association Of Physicians Of India written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Medicine categories.




Neoplasma


Neoplasma
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Author :
language : en
Publisher:
Release Date : 1990

Neoplasma written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Oncology categories.




Schmidt S Jahrbuecher


Schmidt S Jahrbuecher
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Author :
language : en
Publisher:
Release Date : 1899

Schmidt S Jahrbuecher written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1899 with categories.