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Selective Serotonin Reuptake Inhibitors Ssris For Major Depression
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Author : Devidas Menon
language : en
Publisher:
Release Date : 1997
Selective Serotonin Reuptake Inhibitors Ssris For Major Depression written by Devidas Menon and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Medical categories.
Recent years have witnessed large increase in expenditures on antidepressants. This has coincided with the introduction and the widespread use of a new class of antidepressants, the selective serotonin reuptake inhibitors (SSRIs). SSRIs are substantially more expensive than the older tricyclic antidepressants (TCAs), but have a different adverse effect profile and are better tolerated. This study examines the cost-effectiveness of this new class of antidepressants as compared to TCAs in the outpatient treatment of depression. A decision model is built in order to compare three different strategies. The first strategy consists of an SSRI followed by a TCA in case of failure, the second strategy consists of a TCA followed by an SSRI in case of failure, and the third strategy consists of TCA only. The model indicates that the success rate of a short term treatment with an SSRI is higher than one with a TCA, but is also more expensive. However, as maintenance therapy is initiated, and the switch of medications is allowed for those who drop out of treatment, the cumulative success rate of SSRI first strategy becomes very similar to that of the TCA first strategy, but the cost of the SSRI first strategy increases over time. In comparison, when estimates of drop-out rates taken from studies conducted in naturalistic environments are substituted for clinical trial rates, this additional cost becomes increasingly small. If quality of life is considered, the SSRI first strategy offers improved quality of life over the TCA first strategy. In other words, an SSRI first-line strategy is dominant over a TCA only strategy, and an SSRI first-line strategy compared to a SSRI second-line strategy produces QALYs at an acceptable cost by current standards.
Selective Serotonin Reuptake Inhibitors Ssris
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Author : S. Clare Stanford
language : en
Publisher: Landes Bioscience
Release Date : 1999
Selective Serotonin Reuptake Inhibitors Ssris written by S. Clare Stanford and has been published by Landes Bioscience this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.
Details advantages and disadvantages of SSRIs. Starts with a personal memoir of the discovery of the first SSRI, then looks at SSRIs from the clinical point of view. Later chapters concentrate on preclinical material. A final chapter makes pharmacological and clinical comparisons between the tricycl
Ssris In Depression And Anxiety
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Author : S. A. Montgomery
language : en
Publisher: Wiley-Blackwell
Release Date : 2001-07-09
Ssris In Depression And Anxiety written by S. A. Montgomery and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-07-09 with Medical categories.
"SSRIs in Depression and Anxiety, Second Edition, will provide a timely update on the use of SSRIs as their application in this area becomes more widespread
Selective Serotonin Reuptake Inhibitors Ssris For Major Depression
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Author : Evelinda Trindade
language : en
Publisher:
Release Date : 1997
Selective Serotonin Reuptake Inhibitors Ssris For Major Depression written by Evelinda Trindade and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Antidepressants categories.
162 randomized controlled trials that compare selective serotonin reuptake inhibitors (SSRIs) to placebo or other antidepressants were reviewed. Meta-analyses were undertaken to compare 1) efficacy, 2) completion rates, and 3) adverse effects of individual drugs and drug classes. Efficacy was not statistically significantly different among individual SSRIs or between SSRIs as a group and tricyclic antidepressants (TCAs) or other antidepressants. SSRIs were significantly more efficacious than placebo. Completion rates were not statistically significantly different among individual SSRIs or between SSRIs as a group and TCAs or other antidepressants. Completion rates with SSRIs were significantly better than with placebo. Differences in drop-outs (between SSRIs and TCAs) due to lack of effect or worsening of symptoms were not statistically significantly different. Neither were the differences in drop-out rates due to adverse events, except when adult and outpatient group were combined. SSRIs were shown to be associated with statistically significantly more: nausea, anorexia, diarrhea, anxiety, agitation, insomnia and nervousness than TCAs. On the other hand, patients on SSRIs have statistically significantly fewer rates of: dry mouth, constipation, blurred vision and dizziness than with TCAs.
Ssris In Depression And Anxiety
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Author : Stuart A. Montgomery
language : en
Publisher:
Release Date : 1998-10-15
Ssris In Depression And Anxiety written by Stuart A. Montgomery and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-10-15 with Medical categories.
Perspectives in Psychiatry Volume 7 SSRIs in Depression and Anxiety Edited by Stuart A. Montgomery Imperial College, London, UK and Johan A. den Boer Groningen University, The Netherlands The therapeutic profile of SSRIs, shown to work in the treatment of depression, has now been expanded to treat anxiety. Written to fill the current research gap and reflect a topical subject of growing importance, this timely volume explains the origins of anxiety, its biological basis, how it relates to depression and various anxiety disorders and phobias. The book also describes the biological and clinical effects of SSRIs on such conditions, providing readers with an international perspective and up-to-date source of information from experts in this field. This highly topical book discusses: The epidemiology of depression and anxiety disorders; the biological aspects of anxiety disorders and depression; comorbidity of depression and anxiety disorders; the utility of SSRIs in anxious depression; SSRIs in the treatment of panic disorder; SSRIs in social phobia with or without major depression; SSRIs in obsessive-compulsive disorder; serotonin and serotonergic drugs in post-traumatic stress disorder.
Prevalence Of Selective Serotonin Reuptake Inhibitors In Pilot Fatalities Of Civil Aviation Accidents 1990 2001
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Author : Ahmet Akin
language : en
Publisher:
Release Date : 2003
Prevalence Of Selective Serotonin Reuptake Inhibitors In Pilot Fatalities Of Civil Aviation Accidents 1990 2001 written by Ahmet Akin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Aircraft accidents categories.
The Physician S Guide To Depression And Bipolar Disorders
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Author : Dwight L. Evans
language : en
Publisher: McGraw-Hill Education / Medical
Release Date : 2006
The Physician S Guide To Depression And Bipolar Disorders written by Dwight L. Evans and has been published by McGraw-Hill Education / Medical this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical categories.
This concise, results-oriented guidebook is designed to aid the physician in detecting, diagnosing, and treating depression and bipolar disorders. This resource also addresses how these disorders coexist with medical illnesses and what the impact is. This book's prescriptive approach offers clear, definitive instructions on drug treatment for each disorder, with the exact dosages.
Managing Negative Symptoms Of Schizophrenia
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Author : Ann Mortimer
language : en
Publisher: Science Press Incorporated
Release Date : 2001
Managing Negative Symptoms Of Schizophrenia written by Ann Mortimer and has been published by Science Press Incorporated this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Medical categories.
Dipiro S Pharmacotherapy Handbook 12th Edition
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Author : Terry L. Schwinghammer
language : en
Publisher: McGraw Hill Professional
Release Date : 2023-08-04
Dipiro S Pharmacotherapy Handbook 12th Edition written by Terry L. Schwinghammer and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-04 with Medical categories.
The drug information you need to pass the boards and make effective drug therapy decisions―all in one convenient portable guide Expertly written and easy to read, Pharmacotherapy Handbook delivers key content for students studying for their boards, and it offers the essential information required for effective clinical practice. While it’s concise enough to read quickly, it provides ample background information about drug therapy—making it a highly effective study tool. Pharmacotherapy Handbook covers 140+ diseases and disorders most commonly encountered in a clinical setting. Each chapter is organized in a consistent format: • Disease state definition •Pathophysiology • Clinical presentation • Diagnosis • Treatment • Evaluation of therapeutic outcomes Providing a thorough understanding about what drugs to use and why, this unmatched guide includes flowcharts, tables, and charts, provides JNC-VI drug therapy and pharmaceutical care guidelines, and offers concise chapter summaries that save precious study time.
Clinical Handbook Of Psychotropic Drugs
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Author : Kalyna Z. Bezchlibnyk-Butler
language : en
Publisher: Hogrefe & Huber Publishing
Release Date : 2003
Clinical Handbook Of Psychotropic Drugs written by Kalyna Z. Bezchlibnyk-Butler and has been published by Hogrefe & Huber Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Medical categories.
This reference is aimed at everyone who needs an up-to-date, easy-to-use, comprehensive summary of all the most relevant information about psychotropic drugs. Over its previous 12 editions, the Clinical Handbook of Psychotropic Drugs has gained a reputation among all mental health professionals for helping them to: keep up to date on approved and off-label indications; find clear advice for patients about medication options and precautions; look up details of a range of treatment options in easy-to-read comparison charts; check up on the precautions needed in the young, the elderly, or pregnant patients; and see potential interactions and side effects at a glance. drugs such as Escitalopram, Atomoxetine, Oxcarbazepine, and Aripiprazole, and has new findings on recent drugs. Chapters on Bright Light Therapy (BLT) and Repetitive Transcranial Magnetic Stimulation (rTMS) have been included.