Risk Analysis For Development Applications
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Development Of Risk Assessment Methodology For Land Application And Distribution And Marketing Of Municipal Sludge
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Author :
language : en
Publisher:
Release Date : 1989
Development Of Risk Assessment Methodology For Land Application And Distribution And Marketing Of Municipal Sludge written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Health risk assessment categories.
Egfr Tkis For Lung Cancer Treatment Development Application And Side Effects
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Author : Qinglin Shen
language : en
Publisher: Frontiers Media SA
Release Date : 2025-06-03
Egfr Tkis For Lung Cancer Treatment Development Application And Side Effects written by Qinglin Shen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-03 with Medical categories.
Lung cancer is the malignant tumor with the highest incidence and mortality rate in the world. With the in-depth research of molecular biology and the development of targeted drugs, targeted therapy has changed the pattern of lung cancer treatment. In 2004, mutations in the epidermal growth factor receptor (EGFR) were discovered and successfully combined with the development of small molecule tyrosine kinase inhibitors (TKIs), ushering in the era of targeted therapy for non-small cell lung cancer (NSCLC). After nearly 20 years of development, three generations of EGFR-TKIs have been widely used in clinical practice, bringing significant benefits to patients, prolonging survival, and improving quality of life. Molecular targeted therapy has good molecular selectivity, which can efficiently and selectively kill tumor cells, and reduce damage to normal tissues. The adverse reactions of EGFR-TKIs treatment for lung cancer are different from those of traditional treatments such as surgery, radiotherapy, and chemotherapy. Targeted therapy has completely changed the diagnosis and treatment mode of lung cancer and improved the quality of life of patients. However, targeted therapy will eventually lead to drug resistance and more or less adverse reactions during the treatment process. The efficacy and safety of EGFR-TKIs in the treatment of lung cancer remain of utmost importance. Besides the three generations EGFR-TKIs that have already been clinically applied, we urgently need to develop novel efficient, and low-toxicity EGFR-TKIs. Therefore, we expect to explore the development, application, and side effects of EGFR-TKIs for lung cancer. So as to extend the overall survival and improve the quality of life. The focus of this Research Topic is to explore the EGFR-TKIs treatment for lung cancer. These may include, but are not limited to: 1. Development of EGFR-TKIs of lung cancer 2. Application of EGFR-TKIs to lung cancer 3. Side effects of EGFR-TKIs of lung cancer Please note: Manuscripts consisting solely of bioinformatics, computational analysis, or predictions of public databases which are not accompanied by validation (independent clinical or patient cohort, or biological validation in vitro or in vivo, which are not based on public databases) are not suitable for publication in this journal.
Patterns Models And Application Development
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Author : Julio Sanchez
language : en
Publisher: CRC Press
Release Date : 1997-10-24
Patterns Models And Application Development written by Julio Sanchez and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-10-24 with Computers categories.
Patterns, Models, and Application Development, a new book from two experts in C++, integrates a methodology for program development and covers three main categories: object modeling as a program design tool, design patterns and their modeling in C++ language structures, and a discussion of the implementation of PC hardware-related features. It addresses the gap between the ability to code and the ability to program.
Application Development And Design Concepts Methodologies Tools And Applications
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Author : Management Association, Information Resources
language : en
Publisher: IGI Global
Release Date : 2017-08-11
Application Development And Design Concepts Methodologies Tools And Applications written by Management Association, Information Resources and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-11 with Computers categories.
Advancements in technology have allowed for the creation of new tools and innovations that can improve different aspects of life. These applications can be utilized across different technological platforms. Application Development and Design: Concepts, Methodologies, Tools, and Applications is a comprehensive reference source for the latest scholarly material on trends, techniques, and uses of various technology applications and examines the benefits and challenges of these computational developments. Highlighting a range of pertinent topics such as software design, mobile applications, and web applications, this multi-volume book is ideally designed for researchers, academics, engineers, professionals, students, and practitioners interested in emerging technology applications.
Scientific Review Of The Proposed Risk Assessment Bulletin From The Office Of Management And Budget
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2007-04-16
Scientific Review Of The Proposed Risk Assessment Bulletin From The Office Of Management And Budget written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-16 with Political Science categories.
Risk assessments are often used by the federal government to estimate the risk the public may face from such things as exposure to a chemical or the potential failure of an engineered structure, and they underlie many regulatory decisions. Last January, the White House Office of Management and Budget (OMB) issued a draft bulletin for all federal agencies, which included a new definition of risk assessment and proposed standards aimed at improving federal risk assessments. This National Research Council report, written at the request of OMB, evaluates the draft bulletin and supports its overall goals of improving the quality of risk assessments. However, the report concludes that the draft bulletin is "fundamentally flawed" from a scientific and technical standpoint and should be withdrawn. Problems include an overly broad definition of risk assessment in conflict with long-established concepts and practices, and an overly narrow definition of adverse health effects-one that considers only clinically apparent effects to be adverse, ignoring other biological changes that could lead to health effects. The report also criticizes the draft bulletin for focusing mainly on human health risk assessments while neglecting assessments of technology and engineered structures.
New Technologies Development And Application Iii
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Author : Isak Karabegović
language : en
Publisher: Springer Nature
Release Date : 2020-05-04
New Technologies Development And Application Iii written by Isak Karabegović and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-04 with Technology & Engineering categories.
This proceedings book features papers presented at the International Conference on New Technologies, Development and Application, held at the Academy of Sciences and Arts of Bosnia and Herzegovina in Sarajevo on 25th–27th June 2020. It covers a wide range of future technologies and technical disciplines, including complex systems such as Industry 4.0; patents in Industry 4.0; robotics; mechatronics systems; automation; manufacturing; cyber-physical and autonomous systems; sensors; networks; control; energy and renewable energy sources; automotive and biological systems; vehicular networking and connected vehicles; effectiveness and logistics systems; smart grids; nonlinear systems; power; social and economic systems; education; and IoT. The book focuses on the Fourth Industrial Revolution “Industry 4.0,” in which implementation will improve many aspects of human life in all segments and lead to changes in business paradigms and production models. Further, new business methods are emerging, transforming production systems, transport, delivery, and consumption, which need to be monitored and implemented by every company involved in the global market.
Hydro Environmental Analysis
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Author : James L. Martin
language : en
Publisher: CRC Press
Release Date : 2013-12-04
Hydro Environmental Analysis written by James L. Martin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-04 with Science categories.
Focusing on fundamental principles, Hydro-Environmental Analysis: Freshwater Environments presents in-depth information about freshwater environments and how they are influenced by regulation. It provides a holistic approach, exploring the factors that impact water quality and quantity, and the regulations, policy and management methods that are necessary to maintain this vital resource. It offers a historical viewpoint as well as an overview and foundation of the physical, chemical, and biological characteristics affecting the management of freshwater environments. The book concentrates on broad and general concepts, providing an interdisciplinary foundation. The author covers the methods of measurement and classification; chemical, physical, and biological characteristics; indicators of ecological health; and management and restoration. He also considers common indicators of environmental health; characteristics and operations of regulatory control structures; applicable laws and regulations; and restoration methods. The text delves into rivers and streams in the first half and lakes and reservoirs in the second half. Each section centers on the characteristics of those systems and methods of classification, and then moves on to discuss the physical, chemical, and biological characteristics of each. In the section on lakes and reservoirs, it examines the characteristics and operations of regulatory structures, and presents the methods commonly used to assess the environmental health or integrity of these water bodies. It also introduces considerations for restoration, and presents two unique aquatic environments: wetlands and reservoir tailwaters. Written from an engineering perspective, the book is an ideal introduction to the aquatic and limnological sciences for students of environmental science, as well as students of environmental engineering. It also serves as a reference for engineers and scientists involved in the management, regulation, or restoration of freshwater environments.
Advances In Government Enterprise Architecture
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Author : Saha, Pallab
language : en
Publisher: IGI Global
Release Date : 2008-11-30
Advances In Government Enterprise Architecture written by Saha, Pallab and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-30 with Law categories.
Presents current developments, issues, and trends in enterprise architecture (EA). Provides insights into the impact of effective EA on IT governance, IT portfolio management, and IT outsourcing.
Journal Of Mechanical Design
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Author :
language : en
Publisher:
Release Date : 2008
Journal Of Mechanical Design written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Engineering design categories.
Risk Characterization For Food Additives And Contaminants
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Author : Josephine Album Mauskopf
language : en
Publisher:
Release Date : 1990
Risk Characterization For Food Additives And Contaminants written by Josephine Album Mauskopf and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Environmental health categories.